Entera Bio

Entera Bio

ENTX
Jerusalem, Israel· Est.
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ENTX · Stock Price

USD 1.37-0.78 (-36.28%)
Market Cap: $69.7M

Historical price data

Market Cap: $69.7MPipeline: 6 drugsFounded: 2010HQ: Jerusalem, Israel

Overview

Entera Bio is a clinical-stage biotech focused on transforming injectable peptide therapies into convenient oral tablets using its proprietary N-Tab® drug delivery platform. The company's strategy de-risks development by targeting well-characterized peptides like PTH, with its lead asset, EB613 for osteoporosis, having completed a positive Phase 2 study and a streamlined Phase 3 protocol submitted in early 2026. Backed by a seasoned management team and strategic partnerships, Entera aims to redefine standards of care by improving patient adherence and enabling earlier therapeutic intervention.

Metabolic Bone DiseasesEndocrinologyObesity & Metabolic DiseasesGastrointestinal

Technology Platform

The N-Tab® platform is a proprietary oral drug delivery technology that co-formulates therapeutic peptides with GRAS excipients to stabilize the molecule in the GI tract and transiently enhance intestinal permeability for systemic absorption.

Pipeline

6
6 drugs in pipeline
DrugIndicationStageWatch
EnteraBio's Oral Parathyroid Hormone (1-34)HypoparathyroidismPhase 2
EBP05 + Placebo of EBP05OsteoporosisPhase 2
EB612 (EBP05) + NATPARA/NATPARHypoparathyroidismPhase 2
EBP05 + Forteo 0.02 mg + EBP11 + EBP22 + EBP11-F2 + EBP11-F4...HypoparathyroidismPhase 1
Teriparatide + Oral PTH (1-34)Drug Safety and BioavailabilityPhase 1

Funding History

3
Total raised:$37M
PIPE$10M
IPO$15M
Series A$12M

Opportunities

Entera's lead oral anabolic for osteoporosis (EB613) addresses a multi-billion dollar market with no oral competitors, offering a paradigm shift in treatment convenience.
Success would validate its platform, creating significant value for its pipeline in obesity and rare diseases, potentially attracting partnership or acquisition interest.

Risk Factors

The company faces high clinical risk as EB613 enters pivotal Phase 3 trials, alongside significant financing needs to complete development.
It also competes in crowded markets (e.g., obesity) against large pharma companies with substantial resources.

Competitive Landscape

Entera's primary competition varies by program: injectable anabolics in osteoporosis, conventional therapy in hypoparathyroidism, and injectable GLP-1 agonists in obesity. Its key differentiator is the oral tablet format, protected by a strong IP portfolio around its N-Tab® platform.

Company Timeline

2010Founded

Founded in Jerusalem, Israel

2016Series A

Series A: $12.0M

2018IPO

IPO — $15.0M

2021PIPE

PIPE: $10.0M