Compugen

Compugen

CGEN
Holon, Israel· Est.
Is this your company? Claim your profile to update info and connect with investors.
Claim profile

CGEN · Stock Price

USD 2.86+1.60 (+126.98%)
Market Cap: $271.4M

Historical price data

Overview

Compugen is a computational discovery-driven biotech focused on identifying and developing first-in-class cancer immunotherapies. Its core asset is the proprietary, AI/ML-powered Unigen™ platform, which integrates multi-omics data to predict novel immune checkpoints and therapeutic targets. The company has successfully translated its computational predictions into a clinical pipeline, with multiple programs in Phase 1/2 development. Its strategy is to advance these assets independently or through strategic partnerships to address significant unmet needs in oncology.

OncologyImmuno-oncology

Technology Platform

The Unigen™ platform is an AI/ML-powered computational discovery engine that integrates multi-omics data to systematically predict novel immune checkpoints and therapeutic targets in immuno-oncology, operating as a continuous learning system.

Pipeline

2
2 drugs in pipeline
DrugIndicationStageWatch
COM701 + Normal SalineOvarian CancerPhase 1/2
Dose escalation: COM902 monotherapy. + Cohort expansion: COM...Advanced CancerPhase 1

Funding History

3
Total raised:$105M
PIPE$35M
PIPE$40M
IPO$30M

Opportunities

Positive clinical data from its novel PVRIG/TIGIT/PD-1 combination could address a large market of patients resistant to current immunotherapies, driving significant partnership or acquisition interest.
The validated Unigen™ platform provides a sustainable engine for generating new first-in-class assets, creating long-term pipeline optionality.

Risk Factors

Lead clinical programs are high-risk, first-in-class assets with unproven efficacy, and failure would significantly impact valuation.
The company faces intense competition from large pharma and well-funded biotechs in the crowded immuno-oncology space, challenging market adoption.

Competitive Landscape

Competes with large pharma developing next-gen IO combinations and a growing field of biotechs targeting the myeloid compartment. Differentiates through its computationally-derived novel targets (e.g., PVRIG), first-mover advantage in developing them, and its proprietary, validated AI/ML discovery platform.