Alpha Tau Medical

Alpha Tau Medical

DRTSPre-clinical

Alpha Tau Medical is developing a breakthrough alpha-radiation therapy for solid tumors, with its core Alpha DaRT technology originating from Tel Aviv University in 2003. The company is now in clinical execution mode, with multiple active, recruiting trials across seven cancer types at leading global cancer centers. Its strategic focus is on demonstrating efficacy and safety across a diverse oncology portfolio to address significant unmet needs in both accessible and hard-to-treat tumors.

Market Cap
$622.2M
Focus
Radiopharmaceuticals

DRTS · Stock Price

USD 7.076.71 (-48.69%)

Historical price data

AI Company Overview

Alpha Tau Medical is developing a breakthrough alpha-radiation therapy for solid tumors, with its core Alpha DaRT technology originating from Tel Aviv University in 2003. The company is now in clinical execution mode, with multiple active, recruiting trials across seven cancer types at leading global cancer centers. Its strategic focus is on demonstrating efficacy and safety across a diverse oncology portfolio to address significant unmet needs in both accessible and hard-to-treat tumors.

Technology Platform

Alpha DaRT (Diffusing Alpha-emitters Radiation Therapy): An intratumoral radiotherapy platform using Radium-224-impregnated sources that release short-range, high-energy alpha particles to ablate solid tumors while sparing healthy tissue.

Pipeline Snapshot

1

1 drug in pipeline

DrugIndicationStageWatch
PembrolizumabHead and Neck Squamous Cell CarcinomaPre-clinical

Funding History

2

Total raised: $109M

IPO$80MUndisclosedJul 28, 2021
Series C$29MOurCrowdJan 15, 2020

Opportunities

Alpha Tau's major growth opportunities lie in successfully demonstrating efficacy in hard-to-treat cancers like pancreatic cancer, which represents a blockbuster unmet need.
Furthermore, the platform's applicability across a wide range of solid tumors provides a pipeline-in-a-product opportunity, allowing for rapid expansion into new indications with a validated technology.

Risk Factors

The key risks are clinical failure in ongoing trials, regulatory hurdles for a novel radiotherapy modality, and the significant capital required to fund a broad clinical program and future commercialization.
Competition from established radiotherapy techniques and newer systemic radiopharmaceuticals also poses a market adoption challenge.

Competitive Landscape

Alpha Tau competes with traditional external beam radiotherapy (Varian, Elekta), beta-emitting brachytherapy (Boston Scientific), and systemic targeted radiotherapies (Novartis). Its differentiation is the localized delivery of highly potent alpha radiation, aiming for superior tumor kill with minimal off-target effects compared to these alternatives.

Publications
7
Patents
20
Pipeline
1

Company Info

TypeTherapeutics
LocationIsrael
StagePre-clinical
RevenuePre-revenue

Trading

TickerDRTS
ExchangeNASDAQ

Therapeutic Areas

Oncology

Partners

Tel Aviv UniversityBelinson, Rabin Medical CenterRambam Health Care CampusSheba Medical CenterHadassah HospitalDermatology of Seattle and BellevueUniversity Cancer & Diagnostic Center, HoustonWest Cancer Center & Research InstituteUnity Point HealthUCLACity of HopeBasset HealthcareHoly Name Medical CenterMemorial Sloan Kettering Cancer CenterUniversity of Virginia Health SystemBoca Raton Regional HospitalUniversity of MiamiBaptist Health South Florida MCIDignity Health Cancer InstituteMoffitt Cancer CenterEmory UniversityMayo Clinic RochesterNew Mexico Cancer CenterOhio State University Medical CenterBanner HealthMD Anderson PhoenixIFO - Istituti Fisioterapici OspitalieriCentre Léon BérardCHU Grenoble AlpesTel-Aviv Medical CenterMontefiore Medical CenterCentre Hospitalier de l'Université de Montréal (CHUM)Jewish General Hospital
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