Drug Pipeline Intelligence

Track 54,699 drugs across 686 companies

By Market Cap

🏛️

Big Pharma Pipeline

Where the world's largest pharma companies are investing — pipeline programs from $10B+ companies

22 programs

🥇JNJ-90301900 (NBTXR3) + Cetuximab(Johnson & Johnson)Phase 3

Locally Advanced Head and Neck Squamous Cell Carcinoma

🥈Bumetanide + Furosemide(Johnson & Johnson)Phase 3

Cirrhosis

🥉Xanomeline/Trospium Chloride Capsule + Xanomeline Enteric Capsule + Placebo(Bristol Myers Squibb)Phase 3

Alzheimer Disease

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Mid-Cap Catalyst Watch

Growing companies approaching inflection points — Phase 2+ drugs from $1B-$10B companies

25 programs

🥇Measles-Rubella vaccine (Live) I.P. (Freeze Dried) of M/s. Zydus Lifesciences Ltd + Yellow fever Vaccine (WHO prequalified)(Zydus Lifesciences)Phase 3

Measles

🥈Purified Vi capsular polysaccharide of Salmonella typhi conjugated to tetanus toxoid as carrier protein (Typhoid Vi Conjugate Vaccine I.P.). Trade name: ZyVac® TCV(Zydus Lifesciences)Phase 3

Typhoid Vaccination

🥉HSK39297 + Placebo(Haisco Pharmaceutical Group)Phase 3

IgA Nephropathy (IgAN)

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Small-Cap Pipeline Watch

Hidden gems with breakthrough potential — drugs from companies under $1B that could deliver outsized returns

25 programs

🥇NNZ-2591 + Placebo(Neuren Pharmaceuticals)Phase 3

Phelan-McDermid Syndrome

🥈AVT29 (proposed aflibercept HD biosimilar) + Eylea HD (aflibercept HD)(Alvotech)Phase 3

Diabetic Macular Edema

🥉Firmonertinib + EGFR-TKI inhibitor based on investigator's choice(ArriVent Biopharma)Phase 3

Non-Small-Cell Lung Cancer

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By Therapeutic Area

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Gene & Cell Therapy Watch

The frontier of medicine — gene editing, cell therapy, and viral vector platforms

15 programs

🥇Soquelitinib + Belinostat + Pralatrexate(Corvus Pharmaceuticals)Phase 3

Peripheral T-Cell Lymphoma, Not Otherwise Specified

🥈Avacopan, prednisolone and rituximab + Prednisolone and rituximab(Kissei Pharmaceutical)Approved

ANCA Associated Vasculitis (AAV)

🥉Mogamulizumab(Kyowa Kirin)Approved

Cutaneous T-Cell Lymphoma

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GLP-1 & Metabolic Watch

Obesity, diabetes, and metabolic disease — the hottest therapeutic area in biotech

25 programs

🥇Sotagliflozin + Placebo(Dexcom)Phase 3

Diabetic Nephropathies

🥈Orforglipron + Placebo(Eli Lilly)Phase 3

Obesity

🥉Orforglipron + Placebo(Eli Lilly)Phase 3

Obesity

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Neuroscience Pipeline Watch

Brain and nervous system drugs — Alzheimer's, Parkinson's, depression, and beyond

25 programs

🥇Donanemab + Placebo(Eli Lilly)Phase 3

Alzheimer Disease

🥈Donanemab + Placebo + Dexamethasone(Eli Lilly)Phase 3

Alzheimer's Disease

🥉KarXT + KarX-EC + KarXT + KarX-EC Arm Matching Placebo(Bristol Myers Squibb)Phase 3

Alzheimer Disease

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Oncology Pipeline Watch

Cancer drugs in development — from checkpoint inhibitors to CAR-T and ADCs

25 programs

🥇Niraparib + Temozolomide(Brain Biotech)Phase 3

Glioblastoma

🥈Setidegrasib + Oxaliplatin + Leucovorin + Irinotecan + fluorouracil + liposomal irinotecan + Placebo(Astellas Pharma)Phase 3

Pancreatic Cancer

🥉zolbetuximab + Pembrolizumab + Capecitabine + Oxaliplatin + Folinic acid (leucovorin or local equivalent) + 5-fluorouracil (5-FU) + Placebo(Astellas Pharma)Phase 3

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

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Rare Disease Pipeline Watch

Orphan drugs targeting conditions affecting fewer than 200,000 patients

25 programs

🥇Etavopivat A + Etavopivat B + Etavopivat C(Novo Nordisk)Phase 3

Sickle Cell Disease

🥈SGT-003 + Placebo(Solid Biosciences)Phase 3

Duchenne Muscular Dystrophy

🥉Crizanlizumab + Placebo(Novartis)Phase 3

Sickle Cell Disease

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