Genprex

Genprex

GNPX
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GNPX · Stock Price

USD 0.87-13.38 (-93.93%)
Market Cap: $9.1M

Historical price data

Market Cap: $9.1MPipeline: 4 drugsFounded: 2009HQ: Austin, United States

Overview

Genprex is a clinical-stage biotech focused on developing gene therapies for cancer and diabetes using its proprietary Oncoprex® non-viral delivery platform. The company's strategy centers on advancing its lead candidate, REQORSA, through mid-stage trials in non-small cell and small cell lung cancer, with programs supported by multiple FDA Fast Track and Orphan Drug designations. While still pre-revenue, Genprex aims to address large, underserved patient populations by combining its platform technology with established therapies to overcome treatment resistance.

OncologyMetabolic Disease

Technology Platform

Proprietary non-viral Oncoprex® Nanoparticle Delivery System for systemic gene delivery in oncology, and an AAV-based vector for pancreatic gene delivery in diabetes.

Pipeline

4
4 drugs in pipeline
DrugIndicationStageWatch
quaratusugene ozeplasmid + osimertinib + Platinum-Based Chem...Carcinoma, Non-Small Cell LungPhase 1/2
quaratusugene ozeplasmid + pembrolizumab + docetaxel + ramuc...Non Small Cell Lung CancerPhase 1/2
quaratusugene ozeplasmid + atezolizumabSmall Cell Lung Cancer Extensive StagePhase 1/2
DOTAP:Chol-TUSC2 + Erlotinib + Dexamethasone + Diphenhydrami...Lung CancerPhase 1/2

Funding History

2
Total raised:$22M
PIPE$10M
IPO$12M

Opportunities

Genprex targets multi-billion dollar markets in TKI-resistant NSCLC and maintenance therapy for SCLC, with a unique non-viral gene therapy platform that could enable combination approaches.
Its diabetes program offers a potential paradigm-shifting, one-time treatment for a global epidemic.

Risk Factors

The company faces high clinical trial failure risk, limited cash runway necessitating dilutive financing, and operates in intensely competitive therapeutic areas.
Recent leadership transitions add execution uncertainty.

Competitive Landscape

In oncology, Genprex's non-viral tumor suppressor gene delivery is a key differentiator in a field dominated by viral therapies, cell therapies, and small molecules. In diabetes, its transdifferentiation approach competes with emerging cell replacement and gene editing therapies.

Company Timeline

2009Founded

Founded in Austin, United States

2018IPO

IPO — $12.0M

2021PIPE

PIPE: $10.0M