Genprex
GNPXGNPX · Stock Price
Historical price data
Overview
Genprex is a clinical-stage biotech focused on developing gene therapies for cancer and diabetes using its proprietary Oncoprex® non-viral delivery platform. The company's strategy centers on advancing its lead candidate, REQORSA, through mid-stage trials in non-small cell and small cell lung cancer, with programs supported by multiple FDA Fast Track and Orphan Drug designations. While still pre-revenue, Genprex aims to address large, underserved patient populations by combining its platform technology with established therapies to overcome treatment resistance.
Technology Platform
Proprietary non-viral Oncoprex® Nanoparticle Delivery System for systemic gene delivery in oncology, and an AAV-based vector for pancreatic gene delivery in diabetes.
Pipeline
4| Drug | Indication | Stage | Watch |
|---|---|---|---|
| quaratusugene ozeplasmid + osimertinib + Platinum-Based Chem... | Carcinoma, Non-Small Cell Lung | Phase 1/2 | |
| quaratusugene ozeplasmid + pembrolizumab + docetaxel + ramuc... | Non Small Cell Lung Cancer | Phase 1/2 | |
| quaratusugene ozeplasmid + atezolizumab | Small Cell Lung Cancer Extensive Stage | Phase 1/2 | |
| DOTAP:Chol-TUSC2 + Erlotinib + Dexamethasone + Diphenhydrami... | Lung Cancer | Phase 1/2 |
Funding History
2Opportunities
Risk Factors
Competitive Landscape
In oncology, Genprex's non-viral tumor suppressor gene delivery is a key differentiator in a field dominated by viral therapies, cell therapies, and small molecules. In diabetes, its transdifferentiation approach competes with emerging cell replacement and gene editing therapies.
Competitors
Company Timeline
Founded in Austin, United States
IPO — $12.0M
PIPE: $10.0M