Oncolytics Biotech

Oncolytics Biotech

ONCY
Calgary, Canada· Est.
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ONCY · Stock Price

USD 0.90+0.38 (+73.08%)
Market Cap: $102.8M

Historical price data

Market Cap: $102.8MPipeline: 20 drugs (1 Phase 3)Founded: 1998HQ: Calgary, Canada

Overview

Oncolytics Biotech is singularly focused on developing its first-in-class, intravenously delivered oncolytic reovirus, pelareorep, as a platform immunotherapy for gastrointestinal (GI) tumors. The company has generated compelling clinical data across multiple GI cancers, including metastatic pancreatic ductal adenocarcinoma (mPDAC), KRAS-mutant metastatic colorectal cancer (mCRC), and squamous cell carcinoma of the anus (SCAC), demonstrating survival benefits that significantly exceed historical benchmarks. Its strategy is to advance these programs into registration-focused studies, leveraging Fast Track Designation in pancreatic and colorectal cancer to potentially accelerate the path to market.

OncologyGastrointestinal Cancer

Technology Platform

Pelareorep is a first-in-class, systemically delivered oncolytic reovirus that selectively replicates in RAS-activated tumor cells, inducing immunogenic cell death and priming a potent, durable anti-tumor immune response to convert 'cold' tumors to 'hot'.

Pipeline

20
20 drugs in pipeline1 in Phase 3
DrugIndicationStageWatch
REOLYSIN + Carboplatin + Paclitaxel + PlaceboCarcinoma, Squamous Cell of the Head and NeckPhase 3
Bevacizumab + FOLFIRI + PelareorepRas-mutated Metastatic Colorectal CancerPhase 2
Pemetrexed and Reolysin (and safety run-in) + Pemetrexed + D...Non Small Cell Lung CancerPhase 2
REOLYSIN + Carboplatin + PaclitaxelMetastatic MelanomaPhase 2
REOLYSIN® + Carboplatin + PaclitaxelCarcinoma, Non-small Cell LungPhase 2