Aurinia Pharmaceuticals

Aurinia Pharmaceuticals

AUPH
Victoria, Canada· Est.
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AUPH · Stock Price

USD 15.14+7.14 (+89.25%)
Market Cap: $2.0B

Historical price data

Market Cap: $2.0BPipeline: 18 drugs (9 Phase 3)Patents: 7Founded: 1993HQ: Victoria, Canada

Overview

Aurinia Pharmaceuticals is a Canadian biotech company with a mission to deliver transformative therapies for autoimmune diseases. Its core achievement is the successful FDA approval and commercialization of LUPKYNIS, a first-in-class oral treatment for lupus nephritis. The company's strategy is to maximize the global potential of LUPKYNIS while leveraging its expertise to develop a pipeline of novel candidates, including a dual BAFF/APRIL inhibitor, to build a sustainable, multi-product autoimmune franchise.

Autoimmune DiseasesNephrologyRheumatology

Technology Platform

Next-generation calcineurin inhibitor optimization and dual BAFF/APRIL pathway inhibition for autoimmune diseases.

Pipeline

18
18 drugs in pipeline9 in Phase 3
DrugIndicationStageWatch
Voclosporin + Placebo Oral CapsuleLupus NephritisPhase 3
voclosporinAdolescent Lupus NephritisPhase 3
voclosporin + PlaceboPsoriasisPhase 3
voclosporin + Ciclosporin + PlaceboPsoriasisPhase 3
Voclosporin + Placebo Oral CapsuleAdolescent Lupus NephritisPhase 3

Funding History

2
Total raised:$125M
PIPE$125M
IPOUndisclosed

FDA Approved Drugs

1
LUPKYNISNDAJan 22, 2021

Opportunities

Significant unmet need in lupus nephritis and broader autoimmune diseases provides a large addressable market for LUPKYNIS and pipeline candidates.
Geographic expansion and label extensions for voclosporin, plus the development of the novel dual BAFF/APRIL inhibitor aritinercept, offer multiple pathways for growth.

Risk Factors

Heavy reliance on the commercial success of a single product (LUPKYNIS) amidst growing competition.
Pipeline candidates are early-stage with high clinical development risk.
Recent, sweeping leadership changes introduce execution uncertainty during a critical commercial phase.

Competitive Landscape

LUPKYNIS competes with standard-of-care immunosuppressants (mycophenolate), the biologic belimumab, and off-label use of tacrolimus in lupus nephritis. The broader pipeline will eventually face competition from established and emerging biologic therapies across various autoimmune indications.

Company Timeline

1993Founded

Founded in Victoria, Canada

2009IPO

Initial Public Offering

2017PIPE

PIPE: $125.0M

2021FDA Approval

FDA Approval: LUPKYNIS