Xenon Pharmaceuticals

Xenon Pharmaceuticals

XENE
Vancouver, Canada· Est.
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XENE · Stock Price

USD 56.00+20.98 (+59.91%)
Market Cap: $5.5B

Historical price data

Market Cap: $5.5BPipeline: 23 drugs (11 Phase 3)Patents: 20Founded: 1998HQ: Vancouver, Canada

Overview

Xenon Pharmaceuticals is a Canadian biotech leader dedicated to developing life-changing medicines for neurological and psychiatric conditions. Its core strategy leverages a validated human genetics platform to de-risk ion channel drug discovery, resulting in a deep pipeline of 23 candidates, most notably the Phase 3 Kv7 opener azetukalner for epilepsy and depression. With a market cap of $5.23B and a seasoned leadership team, Xenon is transitioning from a discovery-focused entity to a late-stage clinical company with significant near-term catalysts.

NeurologyPsychiatry

Technology Platform

Proprietary human genetics platform that identifies and validates ion channel targets by studying individuals with extreme phenotypes, de-risking early-stage drug discovery for neurological and psychiatric disorders.

Pipeline

23
23 drugs in pipeline11 in Phase 3
DrugIndicationStageWatch
XEN496EpilepsyPhase 3
XEN1101 + PlaceboFocal Onset SeizuresPhase 3
XEN1101 + PlaceboFocal Onset SeizuresPhase 3
XEN1101 + PlaceboPrimary Generalized Tonic-Clonic SeizuresPhase 3
AzetukalnerBipolar DepressionPhase 3

Funding History

4
Total raised:$270M
PIPE$150M
IPO$60M
Series B$40M
Series A$20M

Opportunities

Near-term Phase 3 readouts in multi-billion dollar markets (epilepsy, depression) offer significant valuation catalysts.
The deep pipeline of ion channel modulators and validated genetics platform provide multiple shots on goal and long-term sustainability.

Risk Factors

High clinical trial failure risk inherent in Phase 3 neuroscience programs.
Transition to a commercial-stage company presents execution challenges in competitive markets.
Reliance on a single lead asset (azetukalner) for near-term value creation.

Competitive Landscape

Faces competition from large pharma and biotech in epilepsy, depression, and pain. Differentiation is rooted in its genetics-validated ion channel targets and novel mechanisms (e.g., Kv7 opening), but commercial success requires outperforming established standards of care.

Company Timeline

1998Founded

Founded in Vancouver, Canada

2007Series B

Series B: $40.0M

2014IPO

IPO — $60.0M

2021PIPE

PIPE: $150.0M