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PBGENE-DMD

Duchenne Muscular Dystrophy (DMD)

Phase 1/2IND Cleared, Trial Initiation Pending

Key Facts

Indication
Duchenne Muscular Dystrophy (DMD)
Phase
Phase 1/2
Status
IND Cleared, Trial Initiation Pending
Company

About Precision BioSciences

Precision BioSciences is a clinical-stage biotech leveraging its proprietary ARCUS genome editing platform to develop potentially curative in vivo therapies for genetic diseases. The company has advanced two wholly-owned programs into Phase 1/2 trials: PBGENE-HBV for chronic Hepatitis B and PBGENE-DMD for Duchenne Muscular Dystrophy, both supported by key regulatory designations. Its strategy combines advancing these core assets with strategic partnerships to validate and fund the ARCUS platform, positioning it in the competitive but high-potential gene editing landscape.

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Other Duchenne Muscular Dystrophy (DMD) Drugs

DrugCompanyPhase
DT-DEC01Dystrogen TherapeuticsPhase 1
Skeletal Muscle Regeneration ProgramIPS HEARTPre-clinical
KYMBEE (deflazacort)Upsher-SmithApproved
ALY688ERAllysta PharmaceuticalsPhase 1
AVGN7 + AVGNDAAVogenPre-clinical
Myomatrix Stabilization ProgramStrykagenPreclinical
RIPPLE™ (implied)SonoTheraPreclinical
Vamorolone (AGAMREE)ReveraGen BioPharmaApproved
AGAMREE (vamorolone)Catalyst PharmaceuticalsMarketed
EDG-5506Edgewise TherapeuticsPhase 2
ELEVIDYS (delandistrogene moxeparvovec-rokl)Sarepta TherapeuticsMarketed / Phase 3
SRP-5051 (vesleteplirsen)Sarepta TherapeuticsPhase 2