Rituximab SC + Rituximab IV + Cyclophosphamide + Doxorubicin + Vincristine + Prednisone/Prednisolone

Phase 3Completed

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Interest: 40/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

Phase 3

Approved

Indication / Disease

Non-Hodgkin's Lymphoma

Conditions

Non-Hodgkin's Lymphoma

Trial Timeline

Feb 15, 2011 → Oct 31, 2017

NCT ID

NCT01200758

About Rituximab SC + Rituximab IV + Cyclophosphamide + Doxorubicin + Vincristine + Prednisone/Prednisolone

Rituximab SC + Rituximab IV + Cyclophosphamide + Doxorubicin + Vincristine + Prednisone/Prednisolone is a phase 3 stage product being developed by Roche for Non-Hodgkin's Lymphoma. The current trial status is completed. This product is registered under clinical trial identifier NCT01200758. Target conditions include Non-Hodgkin's Lymphoma.

What happened to similar drugs?

6 of 20 similar drugs in Non-Hodgkin's Lymphoma were approved

Approved (6) Terminated (3) Active (11)

🔄Bortezomib + Rituximab + RituximabJohnson & JohnsonPhase 3

🔄Zoledronic Acid + Vitamin D + Calcium CarbonateNovartisPhase 3

❌Ofatumumab + Rituximab + Ofatumumab + RituximabNovartisPhase 3

🔄rituximab [MabThera/Rituxan] + Standard chemotherapyRochePhase 3

🔄rituximab [Mabthera/Rituxan]RochePhase 3

🔄Chemotherapy (Induction Period) + RituximabRochePhase 3

✅Chemotherapy + Immunochemotherapy + PegfilgrastimRocheApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01200758	Phase 3	Completed	Feb 15, 2011	Oct 31, 2017	Non-Hodgkin's Lymphoma

Competing Products

20 competing products in Non-Hodgkin's Lymphoma

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ME-401	Kyowa Kirin	Phase 1	29
ME-401	Kyowa Kirin	Phase 2	39
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gemcitabine + cisplatin + dexamethasone	Eli Lilly	Phase 2	35
LY317615	Eli Lilly	Phase 2	35
LY4584180 + Rituximab	Eli Lilly	Phase 1	36
Bortezomib + Rituximab + Rituximab	Johnson & Johnson	Phase 3	40
HRS-3738	Jiangsu Hengrui Medicine	Phase 1	25
SHR1459 ；YY-20394 + SHR1459 ；YY-20394 + Gemcitabine-Oxaliplatin	Jiangsu Hengrui Medicine	Phase 2	31
ABT-199 + Ketoconazole	AbbVie	Phase 1	29
ABT-199 + Rifampin	AbbVie	Phase 1	21
[14C]ABT-199 (GDC-0199)	AbbVie	Phase 1	21
ABT-199 + Rituximab + Bendamustine	AbbVie	Phase 1	29
ABBV-291	AbbVie	Phase 1	36
ABT-199	AbbVie	Phase 1	29
Avelumab	Merck	Phase 1	33