YM155 + Rituximab

Phase 2Completed

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Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Non-Hodgkin's Lymphoma

Conditions

Non-Hodgkin's Lymphoma

Trial Timeline

Nov 1, 2009 → Jun 1, 2015

NCT ID

NCT01007292

About YM155 + Rituximab

YM155 + Rituximab is a phase 2 stage product being developed by Astellas Pharma for Non-Hodgkin's Lymphoma. The current trial status is completed. This product is registered under clinical trial identifier NCT01007292. Target conditions include Non-Hodgkin's Lymphoma.

What happened to similar drugs?

6 of 20 similar drugs in Non-Hodgkin's Lymphoma were approved

Approved (6) Terminated (3) Active (11)

🔄Bortezomib + Rituximab + RituximabJohnson & JohnsonPhase 3

🔄Zoledronic Acid + Vitamin D + Calcium CarbonateNovartisPhase 3

❌Ofatumumab + Rituximab + Ofatumumab + RituximabNovartisPhase 3

🔄rituximab [MabThera/Rituxan] + Standard chemotherapyRochePhase 3

🔄rituximab [Mabthera/Rituxan]RochePhase 3

🔄Chemotherapy (Induction Period) + RituximabRochePhase 3

✅Chemotherapy + Immunochemotherapy + PegfilgrastimRocheApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01007292	Phase 2	Completed	Nov 1, 2009	Jun 1, 2015	Non-Hodgkin's Lymphoma

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20 competing products in Non-Hodgkin's Lymphoma

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LY317615	Eli Lilly	Phase 2	35
LY4584180 + Rituximab	Eli Lilly	Phase 1	36
Bortezomib + Rituximab + Rituximab	Johnson & Johnson	Phase 3	40
HRS-3738	Jiangsu Hengrui Medicine	Phase 1	25
SHR1459 ；YY-20394 + SHR1459 ；YY-20394 + Gemcitabine-Oxaliplatin	Jiangsu Hengrui Medicine	Phase 2	31
ABT-199 + Ketoconazole	AbbVie	Phase 1	29
ABT-199 + Rifampin	AbbVie	Phase 1	21
[14C]ABT-199 (GDC-0199)	AbbVie	Phase 1	21
ABT-199 + Rituximab + Bendamustine	AbbVie	Phase 1	29
ABBV-291	AbbVie	Phase 1	36
ABT-199	AbbVie	Phase 1	29
Avelumab	Merck	Phase 1	33
Pembrolizumab + Flt3L + Poly ICLC	Merck	Phase 1/2	28