rituximab [Mabthera/Rituxan]

Phase 3Completed

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Interest: 40/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

✓

Phase 2

Phase 3

Approved

Indication / Disease

Non-Hodgkin's Lymphoma

Conditions

Non-Hodgkin's Lymphoma

Trial Timeline

Jan 19, 2004 → Jul 21, 2011

NCT ID

NCT01144364

About rituximab [Mabthera/Rituxan]

rituximab [Mabthera/Rituxan] is a phase 3 stage product being developed by Roche for Non-Hodgkin's Lymphoma. The current trial status is completed. This product is registered under clinical trial identifier NCT01144364. Target conditions include Non-Hodgkin's Lymphoma.

What happened to similar drugs?

6 of 20 similar drugs in Non-Hodgkin's Lymphoma were approved

Approved (6) Terminated (3) Active (11)

🔄Bortezomib + Rituximab + RituximabJohnson & JohnsonPhase 3

🔄Zoledronic Acid + Vitamin D + Calcium CarbonateNovartisPhase 3

❌Ofatumumab + Rituximab + Ofatumumab + RituximabNovartisPhase 3

🔄rituximab [MabThera/Rituxan] + Standard chemotherapyRochePhase 3

🔄Chemotherapy (Induction Period) + RituximabRochePhase 3

✅Chemotherapy + Immunochemotherapy + PegfilgrastimRocheApproved

🔄Rituximab SC + Rituximab IV + Cyclophosphamide + Doxorubicin + Vincristine + Prednisone/PrednisoloneRochePhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (10)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01075477	Pre-clinical	Completed	Sep 1, 2009	Dec 1, 2011	Rheumatoid Arthritis
NCT01072240	Pre-clinical	Completed	Sep 1, 2009	Jun 1, 2011	Lymphocytic Leukemia, Chronic
NCT00502840	Phase 3	Completed	Jul 23, 2007	Sep 20, 2011	Rheumatoid Arthritis
NCT00475423	Phase 2	Completed	May 1, 2007	Aug 1, 2011	Idiopathic Thrombocytopenic Purpura
NCT00430352	Approved	Completed	Sep 4, 2006	May 26, 2011	Non-Hodgkin's Lymphoma
NCT00503425	Phase 3	Completed	Jun 30, 2005	May 26, 2013	Rheumatoid Arthritis
NCT01144364	Phase 3	Completed	Jan 19, 2004	Jul 21, 2011	Non-Hodgkin's Lymphoma
NCT01388959	Phase 2	Completed	Nov 1, 1998	Apr 1, 2004	Non-Hodgkin's Lymphoma
NCT01392716	Phase 2	Completed	Oct 1, 1997	Feb 1, 2006	Non-Hodgkin's Lymphoma
NCT01998893	Phase 2	Completed	Jan 1, 1997	Feb 1, 2008	Non-Hodgkin's Lymphoma

Competing Products

20 competing products in Non-Hodgkin's Lymphoma

See all competitors

Product	Company	Stage	Hype Score
YM155 + Rituximab	Astellas Pharma	Phase 2	35
Tazemetostat	Eisai	Phase 2	35
ONTAK	Eisai	Phase 2	35
Tazemetostat	Eisai	Phase 1	29
ME-401	Kyowa Kirin	Phase 1	29
ME-401	Kyowa Kirin	Phase 2	39
gemcitabine	Eli Lilly	Phase 2	27
gemcitabine + cisplatin + dexamethasone	Eli Lilly	Phase 2	35
LY317615	Eli Lilly	Phase 2	35
LY4584180 + Rituximab	Eli Lilly	Phase 1	36
Bortezomib + Rituximab + Rituximab	Johnson & Johnson	Phase 3	40
HRS-3738	Jiangsu Hengrui Medicine	Phase 1	25
SHR1459 ；YY-20394 + SHR1459 ；YY-20394 + Gemcitabine-Oxaliplatin	Jiangsu Hengrui Medicine	Phase 2	31
ABT-199 + Ketoconazole	AbbVie	Phase 1	29
ABT-199 + Rifampin	AbbVie	Phase 1	21
[14C]ABT-199 (GDC-0199)	AbbVie	Phase 1	21
ABT-199 + Rituximab + Bendamustine	AbbVie	Phase 1	29
ABBV-291	AbbVie	Phase 1	36
ABT-199	AbbVie	Phase 1	29
Avelumab	Merck	Phase 1	33