BiotechTube

recombinant human acid alpha-glucosidase (rhGAA)

Phase 2Completed
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Interest: 35/100
35
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Pompe Disease

Conditions

Pompe Disease, Glycogen Storage Disease Type II, Acid Maltase Deficiency Disease, Glycogenosis 2

Trial Timeline

May 1, 2001 → Sep 1, 2002

NCT ID
NCT00025896

About recombinant human acid alpha-glucosidase (rhGAA)

recombinant human acid alpha-glucosidase (rhGAA) is a phase 2 stage product being developed by Sanofi for Pompe Disease. The current trial status is completed. This product is registered under clinical trial identifier NCT00025896. Target conditions include Pompe Disease, Glycogen Storage Disease Type II, Acid Maltase Deficiency Disease.

What happened to similar drugs?

10 of 17 similar drugs in Pompe Disease were approved

Approved (10) Terminated (4) Active (6)
✅alglucosidase alfaSanofiApproved
✅alglucosidase alfaSanofiApproved
✅Alglucosidase alfaSanofiApproved
✅alglucosidase alfaSanofiApproved
✅alglucosidase alfaSanofiApproved
✅Myozyme® (alglucosidase alfa) + Myozyme® (alglucosidase alfa)SanofiApproved
✅ALGLUCOSIDASE ALFASanofiApproved

Hype Score Breakdown

Clinical
12
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT00025896Phase 2Completed

Competing Products

20 competing products in Pompe Disease

See all competitors
ProductCompanyStageHype Score
S-606001 + PlaceboShionogiPhase 2
42
alglucosidase alfaSanofiApproved
43
GZ402666SanofiPhase 1
29
alglucosidase alfa + PlaceboSanofiPhase 3
40
alglucosidase alfaSanofiApproved
43
glucosidase alfaSanofiPre-clinical
26
Alglucosidase alfaSanofiApproved
35
Avalglucosidase AlfaSanofiPhase 2
35
alglucosidase alfaSanofiApproved
43
MyozymeSanofiPhase 3
40
alglucosidase alfaSanofiApproved
43
alglucosidase alfaSanofiPre-clinical
26
Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)SanofiPhase 3
40
Myozyme® (alglucosidase alfa) + Myozyme® (alglucosidase alfa)SanofiApproved
35
ALGLUCOSIDASE ALFASanofiApproved
43
alglucosidase alfa + alglucosidase alfaSanofiApproved
35
Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)SanofiPhase 2
39
MyozymeSanofiPhase 2
35
MyozymeSanofiPhase 2
35
Alglucosidase Alfa + Methotrexate + RituximabSanofiApproved
43