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Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)

Phase 2Active
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Interest: 39/100
39
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Glycogen Storage Disease Type II-Pompe's Disease

Conditions

Glycogen Storage Disease Type II-Pompe's Disease

Trial Timeline

Oct 12, 2017 → Aug 10, 2027

NCT ID
NCT03019406

About Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)

Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829) is a phase 2 stage product being developed by Sanofi for Glycogen Storage Disease Type II-Pompe's Disease. The current trial status is active. This product is registered under clinical trial identifier NCT03019406. Target conditions include Glycogen Storage Disease Type II-Pompe's Disease.

What happened to similar drugs?

3 of 7 similar drugs in Glycogen Storage Disease Type II-Pompe's Disease were approved

Approved (3) Terminated (0) Active (4)
✅ALGLUCOSIDASE ALFA (MYOZYME)SanofiApproved
✅Avalglucosidase alfa (GZ402666)SanofiApproved
✅Avalglucosidase alfaSanofiApproved
🔄avalglucosidase alfaSanofiPhase 3
🔄Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)SanofiPhase 3
🔄Cipaglucosidase alfa + MiglustatAmicus TherapeuticsPhase 3
🔄Oral prednisolone + Placebo for oral prednisoloneUltragenyx PharmaceuticalPhase 3

Hype Score Breakdown

Clinical
12
Activity
12
Company
15
Novelty
0
Community
0

Clinical Trials (2)

NCT IDPhaseStatus
NCT03019406Phase 2Active
NCT02782741Phase 3Completed

Competing Products

20 competing products in Glycogen Storage Disease Type II-Pompe's Disease

See all competitors
ProductCompanyStageHype Score
mRNA-3745ModernaPhase 2
0
alglucosidase alfaSanofiPre-clinical
26
avalglucosidase alfaSanofiPhase 3
44
MyozymeSanofiPhase 2/3
38
MyozymeSanofiPre-clinical
26
Avalglucosidase AlfaSanofiPhase 2
35
MyozymeSanofiPhase 2/3
38
ALGLUCOSIDASE ALFA (MYOZYME)SanofiApproved
43
Avalglucosidase alfa (GZ402666)SanofiApproved
47
Avalglucosidase alfa (GZ402666) + Alglucosidase alfa (GZ419829)SanofiPhase 3
40
Alglucosidase alfaSanofiPhase 2
35
Avalglucosidase alfaSanofiApproved
50
MyozymeSanofiPhase 1/2
32
Alglucosidase alfa GZ419829SanofiPre-clinical
30
alglucosidase alfa (recombinant human acid alpha-glucosidase [rhGAA])SanofiPre-clinical
26
alglucosidase alfaSanofiPre-clinical
26
Cipaglucosidase alfa + MiglustatAmicus TherapeuticsPhase 3
44
BEAM-301: Single dose of BEAM-301 administered by IVBeam TherapeuticsPhase 1/2
33
Oral prednisolone + Placebo for oral prednisoloneUltragenyx PharmaceuticalPhase 3
34
UX053 + Antipyretic + H2 Blocker + H1 BlockerUltragenyx PharmaceuticalPhase 1/2
18