iptacopan

Phase 2Completed
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52
Hype Score

Development Stage

Pre-clinical
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis

Conditions

Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis

Trial Timeline

Apr 9, 2018 → Feb 28, 2022

About iptacopan

iptacopan is a phase 2 stage product being developed by Novartis for Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis. The current trial status is completed. This product is registered under clinical trial identifier NCT03439839. Target conditions include Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis.

Hype Score Breakdown

Clinical
17
Activity
12
Company
10
Novelty
5
Community
5

Clinical Trials (11)

NCT IDPhaseStatus
NCT05222412Pre-clinicalActive
NCT06994845Phase 3Recruiting
NCT06903234Pre-clinicalActive
NCT06797518Phase 2Recruiting
NCT06517758Phase 3Recruiting
NCT05935215Phase 3Recruiting
NCT05630001Phase 3Completed
NCT04889430Phase 3Active
NCT05086744Phase 2Terminated
NCT04747613Phase 3Active
NCT03439839Phase 2Completed

Competing Products

20 competing products in Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis

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Crovalimab + EculizumabChugai PharmaceuticalPhase 3
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Crovalimab + EculizumabChugai PharmaceuticalPhase 3
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RavulizumabAstraZenecaPre-clinical
23
EculizumabAstraZenecaPhase 3
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DanicopanAstraZenecaPhase 3
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LNP023NovartisPre-clinical
23
Iptacopan (LNP023)NovartisPhase 3
77
LNP023NovartisPhase 2
52
IptacopanNovartisPre-clinical
23
IptacopanNovartisPhase 3
77
LNP023 + Eculizumab + RavulizumabNovartisPhase 3
77
LNP023NovartisPhase 3
77
LFG316 + LNP023NovartisPhase 2
52
IptacopanNovartisPhase 3
77
CrovalimabRochePhase 3
77
ABP 959 + EculizumabAmgenPhase 3
76
PegcetacoplanSwedish Orphan BiovitrumPre-clinical
22
BMS-919373 + Placebo (Matching with BMS-919373)Bristol Myers SquibbPhase 2
51
Humanized anti-Factor Bb monoclonal antibody + PlaceboSanofiPhase 1
32