BiotechTube

BMN 349 + Placebo

Phase 1Recruiting
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Interest: 33/100
33
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Alpha 1-Antitrypsin Deficiency

Conditions

Alpha 1-Antitrypsin Deficiency

Trial Timeline

Feb 21, 2025 → Sep 1, 2025

NCT ID
NCT06738017

About BMN 349 + Placebo

BMN 349 + Placebo is a phase 1 stage product being developed by BioMarin Pharmaceutical for Alpha 1-Antitrypsin Deficiency. The current trial status is recruiting. This product is registered under clinical trial identifier NCT06738017. Target conditions include Alpha 1-Antitrypsin Deficiency.

What happened to similar drugs?

2 of 9 similar drugs in Alpha 1-Antitrypsin Deficiency were approved

Approved (2) Terminated (0) Active (7)
✅CE1226CSLApproved
✅Alpha1-proteinase inhibitorCSLApproved
🔄alpha-1 proteinase inhibitor (human)GrifolsPhase 3
🔄Alpha-1 MP + alpha-1 proteinase inhibitor (human)GrifolsPhase 3
🔄Alpha-1 MPGrifolsPhase 3
🔄Alpha-1 MPGrifolsPhase 3
🔄Placebo Matching Mitapivat + MitapivatAgios PharmaceuticalsPhase 3

Hype Score Breakdown

Clinical
6
Activity
15
Company
12
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT06738017Phase 1Recruiting

Competing Products

20 competing products in Alpha 1-Antitrypsin Deficiency

See all competitors
ProductCompanyStageHype Score
Drug-Carbamazepine (Tegretol XR) + Carbamazepine (Tegretol XR) PlaceboNovartisPhase 2
27
BelcesiranNovo NordiskPhase 2
27
belcesiran + PlaceboNovo NordiskPhase 1
29
Belcesiran + Belcesiran + BelcesiranNovo NordiskPhase 2
27
VX-668 + PlaceboVertex PharmaceuticalsPhase 1
29
VX-864 + PlaceboVertex PharmaceuticalsPhase 2
35
VX-634 + PlaceboVertex PharmaceuticalsPhase 1
29
VX-814 + PlaceboVertex PharmaceuticalsPhase 2
27
VX-864Vertex PharmaceuticalsPhase 2
27
SAR447537SanofiPhase 2
42
SAR447537 + ZemairaSanofiPhase 2
35
Alpha-1 Antitrypsin (human)CSLPhase 2
35
CE1226CSLApproved
50
Alpha1-proteinase inhibitorCSLApproved
43
ALN-AAT02 + Placebo + ALN-AAT02Alnylam PharmaceuticalsPhase 1/2
21
ARO-AAT InjectionArrowhead PharmaceuticalsPhase 1
26
ARC-AAT Injection + DiphenhydramineArrowhead PharmaceuticalsPhase 1
18
ARC-AAT InjectionArrowhead PharmaceuticalsPhase 2
24
Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor + Dose of 60 mg/kg alpha1-proteinase inhibitorBaxterPhase 1
26
ARO-AATArrowhead PharmaceuticalsPhase 2
32