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Niraparib + Temozolomide

Phase 3Recruiting
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Interest: 37/100
37
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Glioblastoma

Conditions

Glioblastoma, GBM, Brain Neoplasms, Adult, Malignant, Brain Tumor

Trial Timeline

Jun 19, 2024 → Mar 1, 2028

NCT ID
NCT06388733

About Niraparib + Temozolomide

Niraparib + Temozolomide is a phase 3 stage product being developed by Brain Biotech for Glioblastoma. The current trial status is recruiting. This product is registered under clinical trial identifier NCT06388733. Target conditions include Glioblastoma, GBM, Brain Neoplasms, Adult, Malignant.

What happened to similar drugs?

1 of 17 similar drugs in Glioblastoma were approved

Approved (1) Terminated (1) Active (15)
✅TemozolomideMerckApproved
🔄enzastaurin + lomustineEli LillyPhase 3
🔄DSP-7888 Dosing Emulsion + BevacizumabSumitomo PharmaPhase 3
🔄Temozolomide + Depatuxizumab mafodotin + Placebo for ABT-414AbbViePhase 3
❌Steroid eye drops + Vasoconstrictor eye drops + Ophthalmic steroid ointment + Depatuxizumab mafodotin + TemozolomideAbbViePhase 3
🔄Cediranib + Cediranib + Lomustine Chemotherapy + Placebo CediranibAstraZenecaPhase 3
🔄Cilengitide + TemozolomideMerckPhase 3

Hype Score Breakdown

Clinical
17
Activity
15
Company
5
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT06388733Phase 3Recruiting

Competing Products

20 competing products in Glioblastoma

See all competitors
ProductCompanyStageHype Score
TemferonGenenta SciencePhase 1/2
26
PLX3397 + TemozolomideDaiichi SankyoPhase 1/2
32
PLX3397Daiichi SankyoPhase 2
27
ASP8374 + cemiplimabAstellas PharmaPhase 1
29
Nimotuzumab + TemozolomideSun PharmaceuticalPhase 2
35
Gliadel + Avastin + TemodarEisaiPhase 2
27
BCNU Wafer + Irinotecan + BevacizumabEisaiPhase 1/2
24
KHK2455Kyowa KirinPre-clinical
26
olaratumab + ramucirumabEli LillyPhase 2
35
enzastaurin + temozolomideEli LillyPhase 1/2
32
enzastaurin + bevacizumab + Enzyme-inducing antiepileptic drugs (EIAED) + Non-enzyme inducing antiepileptic drugs (NEIAED)Eli LillyPhase 2
35
Temozolomide + Neratinib + QBS10072S + Abemaciclib + CC-115Eli LillyPhase 2
42
AbemaciclibEli LillyPhase 2
39
Enzastaurin 500 milligram (mg) Once Daily (QD) + Enzastaurin 250 mg Twice Daily (BID)Eli LillyPhase 2
35
Abemaciclib + LY3214996Eli LillyPhase 1
29
enzastaurin + lomustineEli LillyPhase 3
40
Galunisertib + Lomustine + PlaceboEli LillyPhase 2
35
DSP-7888 Dosing Emulsion + BevacizumabSumitomo PharmaPhase 3
40
DSP-7888Sumitomo PharmaPhase 1/2
32
BBI608 + TemozolomideSumitomo PharmaPhase 1/2
32