TSRA-196
Alpha-1 Antitrypsin Deficiency (AATD)
Key Facts
About Tessera Therapeutics
Tessera Therapeutics is a Flagship Pioneering-incubated biotech developing a proprietary 'Gene Writing' platform, which it positions as a new category of genetic medicine beyond traditional gene editing and therapy. The technology is designed to make both small and large, permanent genomic alterations and is coupled with a non-viral delivery system. The company has advanced its lead in vivo program, TSRA-196 for Alpha-1 Antitrypsin Deficiency (AATD), into clinical development, with FDA Fast Track and Orphan Drug designations, and is also pursuing an HIV cure with grant support. As a private, pre-revenue company, Tessera is focused on translating its platform into potentially curative therapies for major unmet medical needs.
View full company profileTherapeutic Areas
Other Alpha-1 Antitrypsin Deficiency (AATD) Drugs
| Drug | Company | Phase |
|---|---|---|
| Unnamed AATD Program | AlveoGene | Pre-clinical |
| NB-101 | Nerai Biosciences | Pre-clinical |
| Undisclosed | GondolaBio | IND Enabling |
| BEAM-302 (for Beam Therapeutics) | Richmond Pharmacology | Phase 1/2 |
| KB408 | Krystal Biotech | Preclinical |
| Alpha-1 Antitrypsin (AAT) | Grifols | Marketed |
| BEAM-302 | Beam Therapeutics | Phase 1/2 |
| GalNAc Program | Korro Bio | Preclinical |