Beam Therapeutics
BEAMBEAM · Stock Price
Historical price data
Overview
Beam Therapeutics is a clinical-stage biotech leader in base editing, a next-generation gene editing technology designed for precise, single-base DNA corrections without double-strand breaks. The company's mission is to deliver durable, one-time cures for serious genetic diseases, with its lead program, BEAM-101 for sickle cell disease and beta-thalassemia, now in Phase 1/2 trials. Beam's strategy leverages a fully integrated platform spanning discovery, development, and in-house GMP manufacturing to build a broad pipeline and establish dominant intellectual property in the precision genetic medicine space.
Technology Platform
Proprietary base editing platform enabling precise, single-letter DNA changes without creating double-strand breaks, utilizing cytosine and adenine base editors for correction, modulation, and multiplexed editing strategies.
Pipeline
7| Drug | Indication | Stage | Watch |
|---|---|---|---|
| BEAM-201 | Lymphoblastic Lymphoma | Phase 1/2 | |
| BEAM-101 | Sickle Cell Disease | Phase 1/2 | |
| BEAM-301: Single dose of BEAM-301 administered by IV | Glycogen Storage Disease Type Ia | Phase 1/2 | |
| BEAM-302 | Alpha 1-Antitrypsin Deficiency | Phase 1/2 | |
| BEAM-103 + Placebo Comparator | Healthy Subjects | Phase 1 |
Funding History
3Opportunities
Risk Factors
Competitive Landscape
Beam competes directly with CRISPR-Cas9 nuclease companies (e.g., CRISPR Therapeutics, Editas), other next-gen editing firms (e.g., Prime Medicine), and gene therapy/oligonucleotide developers. Its primary differentiation is the precision and safety profile of its non-cutting base editors, though it must continuously innovate to maintain its edge in a fast-moving field.
Company Timeline
Founded in Cambridge, United States
Series A: $87.0M
Series B: $135.0M
IPO — $180.0M