SAVM Procedure
Heart Failure with Preserved Ejection Fraction (HFpEF)
Key Facts
About Axon Therapies
Axon Therapies is developing a first-in-class neuromodulation therapy targeting the sympathetic nervous system to address the significant unmet need in heart failure with preserved ejection fraction (HFpEF). Its SAVM procedure, performed with the Satera Ablation System, has shown promising 12-month clinical results from the REBALANCE-HF trial, including improved exercise capacity and quality of life. Founded in 2020 and backed by a $32M Series A round, the company is led by a seasoned medtech executive team and supported by investors like Deerfield Management and Action Potential Venture Capital (GSK). Axon represents a paradigm shift from managing symptoms to treating a proposed root cause of heart failure congestion.
View full company profileTherapeutic Areas
Other Heart Failure with Preserved Ejection Fraction (HFpEF) Drugs
| Drug | Company | Phase |
|---|---|---|
| Barostim™ | CVRx | Clinical Feasibility |
| MANP | E-Star BioTech | Phase 1/2 |
| ALLAY-HF | Alleviant Medical | Pivotal Trial |
| PEGylated Pirfenidone | i-Cordis | Pre-clinical |
| VS-041 | Vasa Therapeutics | Phase 1 |
| Neucardin® | Zensun Sci & Tech | Phase 2 |
| SRD001 (inferred) | Sardocor | Phase 1 |
| STM-01 | Secretome Therapeutics | Phase 1 |