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SAVM Procedure

Heart Failure with Preserved Ejection Fraction (HFpEF)

Phase 2Active

Key Facts

Indication
Heart Failure with Preserved Ejection Fraction (HFpEF)
Phase
Phase 2
Status
Active
Company

About Axon Therapies

Axon Therapies is developing a first-in-class neuromodulation therapy targeting the sympathetic nervous system to address the significant unmet need in heart failure with preserved ejection fraction (HFpEF). Its SAVM procedure, performed with the Satera Ablation System, has shown promising 12-month clinical results from the REBALANCE-HF trial, including improved exercise capacity and quality of life. Founded in 2020 and backed by a $32M Series A round, the company is led by a seasoned medtech executive team and supported by investors like Deerfield Management and Action Potential Venture Capital (GSK). Axon represents a paradigm shift from managing symptoms to treating a proposed root cause of heart failure congestion.

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