Alleviant Medical

Alleviant Medical

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Private Company

Total funding raised: $115.7M

Overview

Alleviant Medical is an innovative, clinical-stage medical device company pioneering a no-implant interatrial shunt therapy for heart failure. Its core technology, the Alleviant System, is a catheter-based device that creates a small, pressure-relieving passage between the heart's atria, aiming to improve symptoms and quality of life for patients who remain symptomatic despite optimal medical therapy. The company is advancing its technology through two pivotal clinical trials and operates as a pre-revenue, private entity backed by venture capital. If successful, Alleviant's implant-free approach could differentiate it in the growing market for heart failure interventional devices.

Cardiovascular

Technology Platform

Catheter-based system for creating an interatrial shunt without a permanent implant, designed to reduce left atrial pressure in heart failure patients.

Funding History

9
Total raised:$115.7M
Grant$499K
Grant$998K
Grant$1.0M
Series B$25M

Opportunities

The massive and growing global heart failure patient population, particularly those with HFpEF where treatment options are limited, presents a significant addressable market.
An implant-free shunt could differentiate from competitors and appeal to clinicians and patients concerned about long-term risks of permanent devices.

Risk Factors

High risk of clinical trial failure in complex, sham-controlled studies.
Significant regulatory hurdles for FDA PMA approval.
Intense competition from other well-funded companies developing interatrial shunt devices, some of which are more advanced.

Competitive Landscape

Alleviant competes in the interatrial shunt space with companies like Corvia Medical (Atrial Shunt Device) and V-Wave (interatrial shunt, partnered with Edwards Lifesciences), which have active clinical programs and CE Marks. It also faces indirect competition from other heart failure device and pharmacotherapy companies. Its key differentiator is the lack of a permanent implant.