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Albumin Shield™-Enabled OV

Undisclosed Solid Tumors

PreclinicalResearch

Key Facts

Indication
Undisclosed Solid Tumors
Phase
Preclinical
Status
Research
Company

About Theriva Biologics

Theriva Biologics is advancing a differentiated oncolytic virus platform engineered for systemic intravenous delivery, a key limitation of earlier therapies. Its lead candidate, VCN-01, has demonstrated promising clinical activity in metastatic pancreatic ductal adenocarcinoma (PDAC) and is positioned for a pivotal Phase 3 trial following a positive End-of-Phase 2 FDA meeting. The company's strategy focuses on leveraging its stroma-degrading and Albumin Shield™ technologies to treat difficult-to-treat solid tumors, both as monotherapy and in combination with chemotherapy and immunotherapy.

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Therapeutic Areas

Other Undisclosed Solid Tumors Drugs

DrugCompanyPhase
Macrophage-Targeting Agonist AntibodyBolt BiotherapeuticsPhase 1
IMA204Immatics BiotechnologiesPhase 1
TAR002TargImmune TherapeuticsPre-clinical
TAR003TargImmune TherapeuticsPre-clinical
ERAS-113ErascaDiscovery
Multiple ProgramsAktis OncologyDiscovery
BAT5506CompugenPreclinical
Precision DACsPrelude TherapeuticsDiscovery
V2ACT ImmunotherapyGeneluxPhase 1
ATOR-4066Alligator Bioscience ABDiscovery/Preclinical
ACR-6840Acrivon TherapeuticsPreclinical
ADC ProgramLantern PharmaDiscovery/Preclinical