Acrivon Therapeutics
ACRVACRV · Stock Price
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Overview
Acrivon Therapeutics is a precision oncology company leveraging its proprietary Acrivon Predictive Precision Proteomics (AP3) platform to develop targeted therapies matched to patients via predictive OncoSignature tests. Its strategy centers on in-licensing and internally developing small molecule inhibitors, with a lead Phase 2 asset, ACR-368, and a dual-inhibitor clinical candidate, ACR-2316. The company aims to improve therapeutic outcomes by directly profiling the functional protein drivers of cancer, a paradigm shift from traditional genomics.
Technology Platform
The Acrivon Predictive Precision Proteomics (AP3) platform uses mass spectrometry-based phosphoproteomics to discover predictive biomarkers and translates them into automated, quantitative OncoSignature companion diagnostic tests for patient selection.
Pipeline
3| Drug | Indication | Stage | Watch |
|---|---|---|---|
| ACR-368 + Gemcitabine | Endometrial Adenocarcinoma | Phase 2 | |
| Gemcitabine + ACR-368 | Head and Neck Squamous Cell Carcinoma | Phase 2 | |
| ACR-2316 | Specific Advanced Solid Tumors | Phase 1 |