Immunocore
IMCRApprovedImmunocore is a UK-based, publicly traded biotech focused on developing transformative T cell receptor-based immunotherapies. Its core achievement is the 2022 launch of KIMMTRAK (tebentafusp), the first-ever approved TCR therapy, for metastatic uveal melanoma. The company is advancing a broad pipeline of bispecific candidates across oncology, virology (HBV, HIV), and autoimmunity using its modular ImmTAX platform, positioning it as a leader in next-generation targeted immunomodulation.
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AI Company Overview
Immunocore is a UK-based, publicly traded biotech focused on developing transformative T cell receptor-based immunotherapies. Its core achievement is the 2022 launch of KIMMTRAK (tebentafusp), the first-ever approved TCR therapy, for metastatic uveal melanoma. The company is advancing a broad pipeline of bispecific candidates across oncology, virology (HBV, HIV), and autoimmunity using its modular ImmTAX platform, positioning it as a leader in next-generation targeted immunomodulation.
Technology Platform
Proprietary ImmTAX platform, a modular bispecific T cell receptor technology that uses an affinity-enhanced TCR to target intracellular disease markers presented by HLA and an anti-CD3 effector to recruit and activate T cells, enabling immune system tuning for cancer, viral infections, and autoimmunity.
Pipeline Snapshot
1717 drugs in pipeline, 3 in Phase 3
| Drug | Indication | Stage |
|---|---|---|
| Brenetafusp + Nivolumab + Nivolumab + Relatlimab | Advanced Melanoma | Phase 3 |
| Tebentafusp + Tebentafusp with Pembrolizumab + Investigators Choice | Advanced Melanoma | Phase 3 |
| Tebentafusp | Uveal Melanoma | Phase 3 |
| Tebentafusp | Uveal Melanoma | Phase 2 |
| IMCgp100 + Dacarbazine + Ipilimumab + Pembrolizumab | Uveal Melanoma | Phase 2 |
Funding History
3Total raised: $618M
FDA Approved Drugs
1Opportunities
Risk Factors
Competitive Landscape
Competes with other TCR therapy developers (Adaptimmune, TScan) and bispecific T cell engager companies. Key differentiation is its first-approved TCR therapy, a proprietary high-affinity TCR discovery platform targeting intracellular proteins, and a modular approach applicable to oncology, virology, and autoimmunity.
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