Immunocore

Immunocore

IMCRApproved

Immunocore is a UK-based, publicly traded biotech focused on developing transformative T cell receptor-based immunotherapies. Its core achievement is the 2022 launch of KIMMTRAK (tebentafusp), the first-ever approved TCR therapy, for metastatic uveal melanoma. The company is advancing a broad pipeline of bispecific candidates across oncology, virology (HBV, HIV), and autoimmunity using its modular ImmTAX platform, positioning it as a leader in next-generation targeted immunomodulation.

Market Cap
$1.5B
Focus
Biologics

IMCR · Stock Price

USD 29.91+1.37 (+4.80%)

Historical price data

AI Company Overview

Immunocore is a UK-based, publicly traded biotech focused on developing transformative T cell receptor-based immunotherapies. Its core achievement is the 2022 launch of KIMMTRAK (tebentafusp), the first-ever approved TCR therapy, for metastatic uveal melanoma. The company is advancing a broad pipeline of bispecific candidates across oncology, virology (HBV, HIV), and autoimmunity using its modular ImmTAX platform, positioning it as a leader in next-generation targeted immunomodulation.

Technology Platform

Proprietary ImmTAX platform, a modular bispecific T cell receptor technology that uses an affinity-enhanced TCR to target intracellular disease markers presented by HLA and an anti-CD3 effector to recruit and activate T cells, enabling immune system tuning for cancer, viral infections, and autoimmunity.

Pipeline Snapshot

17

17 drugs in pipeline, 3 in Phase 3

DrugIndicationStage
Brenetafusp + Nivolumab + Nivolumab + RelatlimabAdvanced MelanomaPhase 3
Tebentafusp + Tebentafusp with Pembrolizumab + Investigators ChoiceAdvanced MelanomaPhase 3
TebentafuspUveal MelanomaPhase 3
TebentafuspUveal MelanomaPhase 2
IMCgp100 + Dacarbazine + Ipilimumab + PembrolizumabUveal MelanomaPhase 2

Funding History

3

Total raised: $618M

IPO$258MUndisclosedFeb 5, 2021
Series B$320MGeneral AtlanticJul 15, 2018
Series A$40MMalin CorporationJan 15, 2015

FDA Approved Drugs

1
KIMMTRAKBLAJan 25, 2022

Opportunities

Significant growth opportunities exist in expanding KIMMTRAK's label, advancing the broad PRAME program (IMC-F106C) into multiple cancer types, and pioneering TCR therapies in large infectious disease markets like HBV (functional cure) and HIV.
The platform's application to autoimmune diseases represents a potentially transformative future frontier.

Risk Factors

Key risks include clinical trial failures for lead pipeline assets, particularly in Phase 3; commercial execution challenges and competition for KIMMTRAK; potential safety issues inherent in potent immune modulation; and the financial burden of funding late-stage development across multiple programs.

Competitive Landscape

Competes with other TCR therapy developers (Adaptimmune, TScan) and bispecific T cell engager companies. Key differentiation is its first-approved TCR therapy, a proprietary high-affinity TCR discovery platform targeting intracellular proteins, and a modular approach applicable to oncology, virology, and autoimmunity.

Publications
20
Patents
20
Pipeline
17
FDA Approvals
1

Company Info

TypeTherapeutics
LocationUnited Kingdom
StageApproved
RevenueRevenue Generating

Trading

TickerIMCR
ExchangeNASDAQ

Therapeutic Areas

OncologyInfectious DiseasesAutoimmune Diseases

Partners

GenentechGSKBill & Melinda Gates FoundationUniversity of Oxford
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