Vir Biotechnology

Vir Biotechnology

VIRPhase 3
San Francisco, United StatesFounded 2016vir.bio

Vir Biotechnology is a public biotech company developing antibody-based therapies for infectious diseases and cancer. Its strategy is built on deep immunology expertise and two core technology platforms: a next-generation antibody platform for infectious diseases and the PRO-XTEN® protease-releasable masking technology for oncology. The company's most advanced program is in Phase 3 for chronic hepatitis delta, and it has demonstrated capability in rapidly advancing candidates, as seen with its COVID-19 and Ebola programs. Vir is led by an experienced management team and board with a track record of drug development and commercialization.

Market Cap
$1.5B
Founded
2016
Focus
AntibodiesBiologicsRNA & Gene Therapy

VIR · Stock Price

USD 9.1012.71 (-58.28%)

Historical price data

AI Company Overview

Vir Biotechnology is a public biotech company developing antibody-based therapies for infectious diseases and cancer. Its strategy is built on deep immunology expertise and two core technology platforms: a next-generation antibody platform for infectious diseases and the PRO-XTEN® protease-releasable masking technology for oncology. The company's most advanced program is in Phase 3 for chronic hepatitis delta, and it has demonstrated capability in rapidly advancing candidates, as seen with its COVID-19 and Ebola programs. Vir is led by an experienced management team and board with a track record of drug development and commercialization.

Technology Platform

Vir utilizes two core platforms: a next-generation antibody platform for infectious diseases to discover and engineer monoclonal antibodies, and the PRO-XTEN® protease-releasable masking technology to create conditionally activated therapeutics for oncology and infectious disease.

Pipeline Snapshot

27

27 drugs in pipeline, 5 in Phase 3

DrugIndicationStage
VIR-7831 + Placebo + RemdesivirCOVID-19Phase 3
sotrovimab + sotrovimab + sotrovimab + sotrovimab + Sotrovimab + Sotrovimab + So...Covid19Phase 3
Tobevibart + Elebsiran + BulevirtideViral HepatitisPhase 3
Tobevibart + ElebsiranViral HepatitisPhase 3
VIR-7831 (sotrovimab) + PlaceboCovid19Phase 2/3

Funding History

4

Total raised: $993M

PIPE$450MSoftBank Vision FundFeb 15, 2021
IPO$143MUndisclosedOct 15, 2019
Series B$250MARCH Venture PartnersDec 15, 2018
Series A$150MARCH Venture PartnersOct 15, 2017

Opportunities

The primary near-term opportunity is capturing the first-mover advantage in the U.S.
market for chronic hepatitis delta therapy, a severe disease with no approved treatment.
Long-term, the PRO-XTEN® platform offers a pipeline-in-a-box opportunity for developing novel, targeted therapies in oncology across multiple tumor types.

Risk Factors

The company faces high clinical risk with its pivotal Phase 3 HDV program, as its valuation is heavily dependent on this single trial.
Pipeline concentration and the early stage of its oncology assets add to development risk, while future competition in the HDV space could intensify.

Competitive Landscape

In hepatitis delta, Vir's main competitors are Gilead (approved in EU) and Eiger BioPharmaceuticals, though the landscape is sparse. Its antibody+masking technology platform competes with other modality-focused biotechs in immuno-oncology. Vir differentiates through its deep immunology expertise and a platform validated by prior regulatory successes in infectious disease.

Publications
18
Patents
10
Pipeline
27

Company Info

TypeTherapeutics
Founded2016
LocationSan Francisco, United States
StagePhase 3
RevenuePre-revenue

Trading

TickerVIR
ExchangeNASDAQ

Therapeutic Areas

Infectious DiseasesOncologyImmunology

Partners

Amunix Pharmaceuticals, Inc. (a Sanofi company)GSK (General Knowledge: COVID-19 collaboration)Ridgeback Biotherapeutics (General Knowledge: Ebola collaboration)
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