Immatics

Immatics

IMTXPhase 3
Tübingen, GermanyFounded 2000immatics.com

Immatics is dedicated to developing transformative T-cell receptor (TCR) therapies to address the significant unmet need in solid tumors. Its core strength lies in its proprietary discovery platforms that identify novel, cancer-specific targets presented by HLA molecules, enabling the development of highly specific TCR-based therapeutics. The company has established strategic partnerships with major players like Bristol Myers Squibb and has multiple clinical-stage assets, including TCR-T cell therapies and TCR Bispecifics, positioning it at the forefront of the next wave of immuno-oncology.

Market Cap
$1.3B
Founded
2000
Employees
250-500
Focus
Biotech

IMTX · Stock Price

USD 9.43+1.95 (+26.07%)

Historical price data

AI Company Overview

Immatics is dedicated to developing transformative T-cell receptor (TCR) therapies to address the significant unmet need in solid tumors. Its core strength lies in its proprietary discovery platforms that identify novel, cancer-specific targets presented by HLA molecules, enabling the development of highly specific TCR-based therapeutics. The company has established strategic partnerships with major players like Bristol Myers Squibb and has multiple clinical-stage assets, including TCR-T cell therapies and TCR Bispecifics, positioning it at the forefront of the next wave of immuno-oncology.

Technology Platform

Proprietary XPRESIDENT® platform for mass spectrometry-based discovery of cancer-specific peptide targets, and ACTengine® platform for developing autologous TCR-engineered T-cell therapies (TCR-T).

Pipeline Snapshot

16

16 drugs in pipeline, 2 in Phase 3

DrugIndicationStage
Sunitinib + GM-CSF + Cyclophosphamide + IMA901Metastatic Renal Cell CarcinomaPhase 3
IMA203 + nivolumab plus relatlimab + lifileucel + nivolumab + pembrolizumab + ip...Melanoma, Cutaneous MalignantPhase 3
Arm A: F16IL2 in combination with paclitaxel + Arm B: PaclitaxelMerkel Cell CarcinomaPhase 2
Endoxana, IMA901, Leukine + IMA901 and LeukineRenal Cell CarcinomaPhase 2
IMA203 Product + IMA203 product- flat dose + IMA203CD8 Product + NivolumabRefractory CancerPhase 1/2

Funding History

4

Total raised: $288.8M

PIPE$110MUndisclosedFeb 15, 2021
IPO$100.8MUndisclosedJul 2, 2020
Series B$58MWellington ManagementJun 15, 2017
Series A$20Mdievini Hopp BioTech holdingJun 15, 2013

Opportunities

Immatics has significant growth opportunities through clinical validation of its lead assets, which could unlock substantial milestone payments from its BMS partnership and enable internal late-stage development.
The broad applicability of its targets (PRAME, MAGEA4/8) across multiple high-incidence solid tumors presents a large addressable market.
Success in its bispecific programs could lead to faster-to-market, off-the-shelf products with easier commercialization.

Risk Factors

Key risks include clinical trial failures due to efficacy or safety issues, the inherent complexity and high cost of manufacturing personalized cell therapies, and intense competition in the TCR space from better-funded rivals.
The company's reliance on specific HLA subtypes (like HLA-A*02:01) limits the treatable patient population for each therapy.

Competitive Landscape

Immatics faces competition from established TCR players like Adaptimmune and Immunocore, as well as large pharma internal efforts. Its differentiation lies in its proprietary, proteomics-based XPRESIDENT® discovery platform, which aims to identify superior, truly cancer-specific targets, and its balanced pipeline of both cell therapies and off-the-shelf bispecifics.

Publications
20
Patents
3
Pipeline
16

Company Info

TypeTherapeutics
Founded2000
Employees250-500
LocationTübingen, Germany
StagePhase 3
RevenuePre-revenue

Trading

TickerIMTX
ExchangeNASDAQ

Contact

Therapeutic Areas

OncologyImmuno-Oncology

Partners

Bristol Myers Squibb
SIMILAR COMPANIES
300Microns
300Microns
Pre-clinical · Munich
BetaSense
BetaSense
Pre-clinical · Berlin
AB Diagnostic Systems
AB Diagnostic Systems
Pre-clinical · Jena
bbi-biotech
bbi-biotech
Pre-clinical · Berlin
Mireca Medicines
Mireca Medicines
Pre-clinical · Munich
Is this your company?

Claim your profile to update information, add pipeline data, and connect with investors.

Claim profile