Immatics
IMTXIMTX · Stock Price
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Overview
Immatics is a clinical-stage biotech company with a mission to develop novel, targeted immunotherapies for solid tumors. Its core achievement is building a dominant, multi-modality pipeline targeting PRAME, an antigen expressed in over 50 cancer types, using its proprietary XPRESIDENT® and XCEPTOR® discovery platforms. The company's strategy is to advance its lead TCR-T cell therapy (IMA203CD8) and bispecific TCR candidates through clinical development, leveraging its transatlantic operational footprint and strategic partnerships to bring precision oncology treatments to a broad patient population.
Technology Platform
Proprietary XPRESIDENT® platform for mass spectrometry-based discovery of cancer-specific peptide targets and XCEPTOR® platform for TCR discovery and engineering.
Pipeline
16| Drug | Indication | Stage | Watch |
|---|---|---|---|
| Sunitinib + GM-CSF + Cyclophosphamide + IMA901 | Metastatic Renal Cell Carcinoma | Phase 3 | |
| IMA203 + nivolumab plus relatlimab + lifileucel + nivolumab ... | Melanoma, Cutaneous Malignant | Phase 3 | |
| Endoxana, IMA901, Leukine + IMA901 and Leukine | Renal Cell Carcinoma | Phase 2 | |
| Arm A: F16IL2 in combination with paclitaxel + Arm B: Paclit... | Merkel Cell Carcinoma | Phase 2 | |
| Endoxana, Leukine, IMA910 + Endoxana, Leukine, IMA910, Aldar... | Colorectal Carcinoma | Phase 1/2 |
Funding History
4Opportunities
Risk Factors
Competitive Landscape
Immatics is the clinical leader in PRAME-targeted therapies, with few direct competitors at a similar stage. It competes broadly with other TCR-focused companies (e.g., Adaptimmune, Immunocore) and CAR-T developers moving into solid tumors. Its proprietary discovery platforms and deep PRAME focus are key differentiators.
Company Timeline
Founded in Tübingen, Germany
Series B: $58.0M
IPO — $100.8M
PIPE: $110.0M