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zolbetuximab + oxaliplatin + capecitabine + placebo

Phase 3Active
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77
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Conditions

Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer, Metastatic Gastroesophageal Junction (GEJ) Adenocarcinoma

Trial Timeline

Nov 28, 2018 → Sep 30, 2026

NCT ID
NCT03653507

About zolbetuximab + oxaliplatin + capecitabine + placebo

zolbetuximab + oxaliplatin + capecitabine + placebo is a phase 3 stage product being developed by Astellas Pharma for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer. The current trial status is active. This product is registered under clinical trial identifier NCT03653507. Target conditions include Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer, Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer, Metastatic Gastric Adenocarcinoma or Cancer.

Hype Score Breakdown

Clinical
27
Activity
18
Company
10
Novelty
9
Community
10

Clinical Trials (1)

NCT IDPhaseStatus
NCT03653507Phase 3Active

Competing Products

20 competing products in Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

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Tadalafil + GemcitabineEli LillyPhase 1
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SPYK04Chugai PharmaceuticalPhase 1
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LUNA18 + CetuximabChugai PharmaceuticalPhase 1
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Trastuzumab + Pertuzumab + Docetaxel + Paclitaxel + Nab-paclitaxel + Vinorelbine + Eribulin + Capecitabine + GemcitabineChugai PharmaceuticalPhase 3
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Trastuzumab Deruxtecan + Cisplatin + Carboplatin + Pembrolizumab + PemetrexedDaiichi SankyoPhase 3
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T-DXd + Durvalumab + Cisplatin + Carboplatin + Pemetrexed + Volrustomig + RilvegostomigDaiichi SankyoPhase 1
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zolbetuximabAstellas PharmaPre-clinical
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enfortumab vedotin + pembrolizumabAstellas PharmaPhase 2
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enfortumab vedotin (EV)Astellas PharmaPre-clinical
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zolbetuximabAstellas PharmaPre-clinical
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ASP3082Astellas PharmaPhase 2
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zolbetuximab + Pembrolizumab + Capecitabine + Oxaliplatin + Folinic acid (leucovorin or local equivalent) + 5-fluorouracil (5-FU) + PlaceboAstellas PharmaPhase 3
77
ASP1948Astellas PharmaPhase 1
33
Camrelizumab + SOX (oxaliplatin + Teggio) /XELOX (oxaliplatin + capecitabine )Sun PharmaceuticalPhase 2
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Camrelizumab and Apatinib Plus GPSun PharmaceuticalPhase 1/2
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