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Vonoprazan

Pre-clinicalRecruiting
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Interest: 27/100
27
Hype Score

Development Stage

1
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Erosive Esophagitis

Conditions

Erosive Esophagitis, Heartburn, Symptomatic Non-erosive Gastroesophageal Reflux Disease, Helicobacter Pylori Infection

Trial Timeline

May 15, 2025 → Sep 1, 2034

NCT ID
NCT06660342

About Vonoprazan

Vonoprazan is a pre-clinical stage product being developed by Phathom Pharmaceuticals for Erosive Esophagitis. The current trial status is recruiting. This product is registered under clinical trial identifier NCT06660342. Target conditions include Erosive Esophagitis, Heartburn, Symptomatic Non-erosive Gastroesophageal Reflux Disease.

What happened to similar drugs?

6 of 13 similar drugs in Erosive Esophagitis were approved

Approved (6) Terminated (0) Active (7)
✅Teprenone capsule and placebo of sucralfate + Sucralfate and placebo of teprenoneEisaiApproved
✅Esomeprazole + LansoprazoleAstraZenecaApproved
✅Esomeprazole + LansoprazoleAstraZenecaApproved
✅Esomeprazole + EsomeprazoleAstraZenecaApproved
✅esomeprazole magnesium (oral medication)AstraZenecaApproved
✅Omeprazole/sodium bicarbonateBausch HealthApproved
🔄E3810 + E3810 + PlaceboEisaiPhase 3

Hype Score Breakdown

Clinical
3
Activity
15
Company
9
Novelty
0
Community
0

Clinical Trials (4)

NCT IDPhaseStatus
NCT06660342Pre-clinicalRecruiting
NCT06391177Phase 1Completed
NCT06106022Phase 1Completed
NCT05343364Phase 1Completed

Competing Products

20 competing products in Erosive Esophagitis

See all competitors
ProductCompanyStageHype Score
YH1885L(Revaprazan) + Esomeprazole 20mg + placeboYuhanPhase 2
35
E3810 + E3810 + PlaceboEisaiPhase 3
40
RABEPRAZOLE SODIUM + RABEPRAZOLE SODIUMEisaiPhase 3
40
Teprenone capsule and placebo of sucralfate + Sucralfate and placebo of teprenoneEisaiApproved
43
ABT-981 + Placebo for ABT-981AbbViePhase 2
35
OmeprazoleAstraZenecaPhase 3
40
Esomeprazole + LansoprazoleAstraZenecaApproved
43
Nexium 20mg + Nexium 10mgAstraZenecaPhase 3
47
OmeprazoleAstraZenecaPhase 3
40
AZD0865AstraZenecaPhase 2
35
Esomeprazole + LansoprazoleAstraZenecaApproved
43
Esomeprazole + EsomeprazoleAstraZenecaApproved
43
AZD0865AstraZenecaPhase 2
35
esomeprazole magnesium (oral medication)AstraZenecaApproved
43
Alendronate Effervescent Oral TabletAmgenPhase 2
35
Omeprazole/sodium bicarbonateBausch HealthApproved
37
VonoprazanPhathom PharmaceuticalsPhase 1
23
Vonoprazan + LansoprazolePhathom PharmaceuticalsPhase 3
34
Vonoprazan + PlaceboPhathom PharmaceuticalsPhase 2
29
Vonoprazan + PlaceboPhathom PharmaceuticalsPhase 3
34