BiotechTube

Vonoprazan

Phase 1Completed
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Interest: 23/100
23
Hype Score

Development Stage

✓
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Erosive Esophagitis

Conditions

Erosive Esophagitis, Heartburn, Symptomatic Nonerosive Gasroesophageal Reflux Disease, Helicobacter Pylori Infection

Trial Timeline

May 7, 2024 → Sep 19, 2024

NCT ID
NCT06391177

About Vonoprazan

Vonoprazan is a phase 1 stage product being developed by Phathom Pharmaceuticals for Erosive Esophagitis. The current trial status is completed. This product is registered under clinical trial identifier NCT06391177. Target conditions include Erosive Esophagitis, Heartburn, Symptomatic Nonerosive Gasroesophageal Reflux Disease.

What happened to similar drugs?

6 of 13 similar drugs in Erosive Esophagitis were approved

Approved (6) Terminated (0) Active (7)
✅Teprenone capsule and placebo of sucralfate + Sucralfate and placebo of teprenoneEisaiApproved
✅Esomeprazole + LansoprazoleAstraZenecaApproved
✅Esomeprazole + LansoprazoleAstraZenecaApproved
✅Esomeprazole + EsomeprazoleAstraZenecaApproved
✅esomeprazole magnesium (oral medication)AstraZenecaApproved
✅Omeprazole/sodium bicarbonateBausch HealthApproved
🔄E3810 + E3810 + PlaceboEisaiPhase 3

Hype Score Breakdown

Clinical
6
Activity
8
Company
9
Novelty
0
Community
0

Clinical Trials (4)

NCT IDPhaseStatus
NCT06660342Pre-clinicalRecruiting
NCT06391177Phase 1Completed
NCT06106022Phase 1Completed
NCT05343364Phase 1Completed

Competing Products

20 competing products in Erosive Esophagitis

See all competitors
ProductCompanyStageHype Score
YH1885L(Revaprazan) + Esomeprazole 20mg + placeboYuhanPhase 2
35
E3810 + E3810 + PlaceboEisaiPhase 3
40
RABEPRAZOLE SODIUM + RABEPRAZOLE SODIUMEisaiPhase 3
40
Teprenone capsule and placebo of sucralfate + Sucralfate and placebo of teprenoneEisaiApproved
43
ABT-981 + Placebo for ABT-981AbbViePhase 2
35
OmeprazoleAstraZenecaPhase 3
40
Esomeprazole + LansoprazoleAstraZenecaApproved
43
Nexium 20mg + Nexium 10mgAstraZenecaPhase 3
47
OmeprazoleAstraZenecaPhase 3
40
AZD0865AstraZenecaPhase 2
35
Esomeprazole + LansoprazoleAstraZenecaApproved
43
Esomeprazole + EsomeprazoleAstraZenecaApproved
43
AZD0865AstraZenecaPhase 2
35
esomeprazole magnesium (oral medication)AstraZenecaApproved
43
Alendronate Effervescent Oral TabletAmgenPhase 2
35
Omeprazole/sodium bicarbonateBausch HealthApproved
37
Vonoprazan + LansoprazolePhathom PharmaceuticalsPhase 3
34
Vonoprazan + PlaceboPhathom PharmaceuticalsPhase 2
29
VonoprazanPhathom PharmaceuticalsPre-clinical
27
Vonoprazan + PlaceboPhathom PharmaceuticalsPhase 3
34