Vericiguat (Verquvo, BAY1021189)
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Interest: 40/100
40
Development Stage
✓
Pre-clinical✓
Phase 1✓
Phase 2✓
Phase 35
ApprovedIndication / Disease
Chronic Heart Failure With Reduced Ejection Fraction
Conditions
Chronic Heart Failure With Reduced Ejection Fraction, Worsening Heart Failure
Trial Timeline
Dec 16, 2022 → Sep 19, 2024
NCT ID
NCT05658458About Vericiguat (Verquvo, BAY1021189)
Vericiguat (Verquvo, BAY1021189) is a approved stage product being developed by Bayer for Chronic Heart Failure With Reduced Ejection Fraction. The current trial status is completed. This product is registered under clinical trial identifier NCT05658458. Target conditions include Chronic Heart Failure With Reduced Ejection Fraction, Worsening Heart Failure.
What happened to similar drugs?
20 of 20 similar drugs in Chronic Heart Failure With Reduced Ejection Fraction were approved
Approved (20) Terminated (3) Active (0)
Hype Score Breakdown
Clinical
20
Activity
8
Company
12
Novelty
0
Community
0
Clinical Trials (5)
| NCT ID | Phase | Status |
|---|---|---|
| NCT06632483 | Pre-clinical | Active |
| NCT06486844 | Pre-clinical | Completed |
| NCT06363110 | Pre-clinical | Completed |
| NCT06148935 | Pre-clinical | Recruiting |
| NCT05658458 | Approved | Completed |
Competing Products
20 competing products in Chronic Heart Failure With Reduced Ejection Fraction
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| Levofloxacin 500 | Dr. Reddy's Laboratories | Pre-clinical | 23 |
| mRNA-0184 | Moderna | Phase 1 | 0 |
| Lubiprostone + Lubiprostone + Placebo | Dr. Reddy's Laboratories | Phase 3 | 37 |
| macitentan 10 mg | BML, Inc. | Phase 3 | 32 |
| KPL-716 + Placebo | Kiniksa Pharmaceuticals | Phase 2 | 29 |
| TERN-701 | Terns Pharmaceuticals | Phase 1/2 | 36 |
| Fludarabine + Cyclophosphamide + PRGN-3007 | Precigen | Phase 1 | 23 |
| LY3556050 + Placebo | Eli Lilly | Phase 2 | 35 |
| THB001 | Third Harmonic Bio | Phase 1 | 11 |
| Briquilimab | Jasper Therapeutics | Phase 1/2 | 26 |
| Briquilimab | Jasper Therapeutics | Phase 1/2 | 14 |
| Briquilimab | Jasper Therapeutics | Phase 2 | 29 |
| Empagliflozin + Matching placebo | Eli Lilly | Phase 3 | 40 |
| LY3461767 + Placebo | Eli Lilly | Phase 1 | 29 |
| Pirtobrutinib + Venetoclax + Rituximab | Eli Lilly | Phase 3 | 44 |
| LY3526318 + Placebo | Eli Lilly | Phase 2 | 35 |
| Pirtobrutinib | Eli Lilly | Phase 2 | 42 |
| Ibrutinib + LY3214996 | Eli Lilly | Phase 1 | 21 |
| Pirtobrutinib + Acalabrutinib | Eli Lilly | Phase 2 | 27 |
| LYR-210 | Lyra Therapeutics | Phase 2 | 25 |