Fludarabine + Cyclophosphamide + PRGN-3007

Phase 1Completed

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Interest: 23/100

Hype Score

Development Stage

✓

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Chronic Lymphocytic Leukemia

Conditions

Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Triple Negative Breast Cancer Malignancies

Trial Timeline

Jan 25, 2023 → Apr 18, 2024

NCT ID

NCT05694364

About Fludarabine + Cyclophosphamide + PRGN-3007

Fludarabine + Cyclophosphamide + PRGN-3007 is a phase 1 stage product being developed by Precigen for Chronic Lymphocytic Leukemia. The current trial status is completed. This product is registered under clinical trial identifier NCT05694364. Target conditions include Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Acute Lymphoblastic Leukemia.

What happened to similar drugs?

20 of 20 similar drugs in Chronic Lymphocytic Leukemia were approved

Approved (20) Terminated (3) Active (0)

✅Pegasys® + Pegasys®Chugai PharmaceuticalApproved

✅Telmisartan/Rosuvastatin 40/10mg + Telmisartan 40mgYuhanApproved

✅placebo + aspirin + clopidogrel + aspirin OR prasugrel + aspirinDaiichi SankyoApproved

✅alefacept + polyvalent pneumococcal vaccineAstellas PharmaApproved

✅alefaceptAstellas PharmaApproved

✅AlefaceptAstellas PharmaApproved

✅lysozyme 90 mg + PlaceboEisaiApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT05694364	Phase 1	Completed	Jan 25, 2023	Apr 18, 2024	Chronic Lymphocytic Leukemia

Competing Products

20 competing products in Chronic Lymphocytic Leukemia

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Briquilimab	Jasper Therapeutics	Phase 2	29
Empagliflozin + Matching placebo	Eli Lilly	Phase 3	40
LY3461767 + Placebo	Eli Lilly	Phase 1	29
Pirtobrutinib + Venetoclax + Rituximab	Eli Lilly	Phase 3	44
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LYR-210	Lyra Therapeutics	Phase 2	25
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