Venetoclax + Azacitidine + Cytarabine + Methotrexate + Hydrocortisone + Leucovorin + Dexamethasone + Vincristine + Doxorubicin + Dexrazoxane + Calaspargase Pegol + Erwinia asparaginase
Phase 1RecruitingDevelopment Stage
Myelodysplastic Syndromes, de Novo
Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary, Myelodysplastic Syndromes, Previously Treated, Treatment-Related Acute Myeloid Leukemia, Therapy-Related Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission, Lymphoblastic Lymphoma, in Relapse, Lymphoblastic Lymphoma, Refractory, Acute Leukemia of Ambiguous Lineage in Relapse, Acute Leukemia of Ambiguous Lineage
Mar 29, 2023 → Jul 2, 2030
About Venetoclax + Azacitidine + Cytarabine + Methotrexate + Hydrocortisone + Leucovorin + Dexamethasone + Vincristine + Doxorubicin + Dexrazoxane + Calaspargase Pegol + Erwinia asparaginase
Venetoclax + Azacitidine + Cytarabine + Methotrexate + Hydrocortisone + Leucovorin + Dexamethasone + Vincristine + Doxorubicin + Dexrazoxane + Calaspargase Pegol + Erwinia asparaginase is a phase 1 stage product being developed by AbbVie for Myelodysplastic Syndromes, de Novo. The current trial status is recruiting. This product is registered under clinical trial identifier NCT05292664. Target conditions include Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary, Myelodysplastic Syndromes, Previously Treated.
Hype Score Breakdown
Clinical Trials (1)
| NCT ID | Phase | Status |
|---|---|---|
| NCT05292664 | Phase 1 | Recruiting |
Competing Products
20 competing products in Myelodysplastic Syndromes, de Novo
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| NEX-18a injection + Azacitidine Injection | Nanexa AB | Phase 1 | 28 |
| JSP191 | Jasper Therapeutics | Phase 1 | 25 |
| Humanized anti-CD117 Monoclonal Antibody (JSP191) | Jasper Therapeutics | Phase 1 | 25 |
| GTB-3550 TriKE® Phase I + GTB-3550 TriKE® Phase II | GT Biopharma | Phase 1/2 | 33 |
| Erlotinib Hydrochloride | Astellas Pharma | Phase 2 | 52 |
| Decitabine + Decitabine + Decitabine | Eisai | Phase 2 | 52 |
| Decitabine + Valproic Acid | Eisai | Phase 2 | 52 |
| decitabine + decitabine | Eisai | Phase 2 | 52 |
| decitabine + azacitidine | Eisai | Approved | 85 |
| Decitabine | Eisai | Phase 2 | 52 |
| decitabine + decitabine + decitabine + decitabine | Eisai | Phase 1 | 33 |
| Decitabine, Arsenic Trioxide and Ascorbic Acid | Eisai | Phase 2 | 52 |
| Subcutaneous Decitabine | Eisai | Phase 1 | 33 |
| Decitabine | Eisai | Phase 2 | 52 |
| Galunisertib + Placebo | Eli Lilly | Phase 2/3 | 65 |
| DSP-7888 | Sumitomo Pharma | Phase 1/2 | 41 |
| TP-0184 | Sumitomo Pharma | Phase 1/2 | 41 |
| Decitabine | Johnson & Johnson | Phase 2 | 52 |
| Epoetin alfa | Johnson & Johnson | Phase 2 | 52 |
| ZARNESTRA, tipifarnib, R115777 | Johnson & Johnson | Phase 2 | 52 |