ZARNESTRA, tipifarnib, R115777

Phase 2Completed

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Interest: 35/100

Hype Score

Development Stage

✓

Pre-clinical

✓

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Myelodysplastic Syndrome

Conditions

Myelodysplastic Syndrome

Trial Timeline

Jul 1, 2002 → May 1, 2006

NCT ID

NCT00050154

About ZARNESTRA, tipifarnib, R115777

ZARNESTRA, tipifarnib, R115777 is a phase 2 stage product being developed by Johnson & Johnson for Myelodysplastic Syndrome. The current trial status is completed. This product is registered under clinical trial identifier NCT00050154. Target conditions include Myelodysplastic Syndrome.

What happened to similar drugs?

7 of 19 similar drugs in Myelodysplastic Syndrome were approved

Approved (7) Terminated (7) Active (7)

✅decitabine + azacitidineEisaiApproved

✅DeferasiroxNovartisApproved

✅ICL670/DeferasiroxNovartisApproved

✅deferasiroxNovartisApproved

✅DeferasiroxNovartisApproved

✅Epoetin betaRocheApproved

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (3)

NCT ID	Phase	Status	Start	Completion	Indication
NCT00050141	Phase 2	Completed	Sep 1, 2002	Jan 1, 2008	Breast Cancer
NCT00050154	Phase 2	Completed	Jul 1, 2002	May 1, 2006	Myelodysplastic Syndrome
NCT00048503	Phase 2	Completed	Jun 1, 2002	Nov 1, 2005	Acute Myeloid Leukemia

Competing Products

20 competing products in Myelodysplastic Syndrome

See all competitors

Product	Company	Stage	Hype Score
NEX-18a injection + Azacitidine Injection	Nanexa AB	Phase 1	23
JSP191	Jasper Therapeutics	Phase 1	11
Humanized anti-CD117 Monoclonal Antibody (JSP191)	Jasper Therapeutics	Phase 1	15
GTB-3550 TriKE® Phase I + GTB-3550 TriKE® Phase II	GT Biopharma	Phase 1/2	14
Erlotinib Hydrochloride	Astellas Pharma	Phase 2	35
Decitabine + Decitabine + Decitabine	Eisai	Phase 2	35
Decitabine + Valproic Acid	Eisai	Phase 2	35
decitabine + decitabine	Eisai	Phase 2	35
decitabine + azacitidine	Eisai	Approved	35
Decitabine	Eisai	Phase 2	27
decitabine + decitabine + decitabine + decitabine	Eisai	Phase 1	29
Decitabine, Arsenic Trioxide and Ascorbic Acid	Eisai	Phase 2	35
Subcutaneous Decitabine	Eisai	Phase 1	21
Decitabine	Eisai	Phase 2	35
Galunisertib + Placebo	Eli Lilly	Phase 2/3	38
DSP-7888	Sumitomo Pharma	Phase 1/2	32
TP-0184	Sumitomo Pharma	Phase 1/2	24
Decitabine	Johnson & Johnson	Phase 2	35
Epoetin alfa	Johnson & Johnson	Phase 2	27
Decitabine	Johnson & Johnson	Phase 2	27