Telaglenastat + Carboplatin Chemotherapy + Pemetrexed Chemotherapy + Pembrolizumab Immunotherapy + Placebo + Dexamethasone 4 mg

Phase 2Terminated
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Interest: 17/100
17
Hype Score

Development Stage

Pre-clinical
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Non-Small Cell Lung Cancer

Conditions

Non-Small Cell Lung Cancer, Non-squamous Non-small-cell Lung Cancer, Non-Squamous Non-Small Cell Neoplasm of Lung, KEAP1 Gene Mutation, NRF2 Gene Mutation, NFE2L2 Gene Mutation

Trial Timeline

Jul 24, 2020 → Feb 9, 2022

About Telaglenastat + Carboplatin Chemotherapy + Pemetrexed Chemotherapy + Pembrolizumab Immunotherapy + Placebo + Dexamethasone 4 mg

Telaglenastat + Carboplatin Chemotherapy + Pemetrexed Chemotherapy + Pembrolizumab Immunotherapy + Placebo + Dexamethasone 4 mg is a phase 2 stage product being developed by Calithera Biosciences for Non-Small Cell Lung Cancer. The current trial status is terminated. This product is registered under clinical trial identifier NCT04265534. Target conditions include Non-Small Cell Lung Cancer, Non-squamous Non-small-cell Lung Cancer, Non-Squamous Non-Small Cell Neoplasm of Lung.

What happened to similar drugs?

20 of 20 similar drugs in Non-Small Cell Lung Cancer were approved

Approved (20) Terminated (2) Active (0)
pemetrexedEli LillyApproved
DurvalumabAstraZenecaApproved
Gefitinib + DocetaxelAstraZenecaApproved
Gefitinib + PlaceboAstraZenecaApproved
PembrolizumabMerckApproved

Hype Score Breakdown

Clinical
12
Activity
0
Company
5
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT04265534Phase 2Terminated

Competing Products

20 competing products in Non-Small Cell Lung Cancer

See all competitors
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35
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32
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37
pemetrexed + cisplatinEli LillyPhase 2
27
CetuximabEli LillyPhase 1
29
pemetrexed + docetaxelEli LillyPhase 3
40
enzastaurin + pemetrexed + docetaxel + carboplatinEli LillyPhase 2
35
PemCarbo + Pem onlyEli LillyPhase 3
36
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35
AdjuvantInsight Molecular DiagnosticsPre-clinical
8
Ramucirumab + Placebo + Erlotinib + Gefitinib + OsimertinibEli LillyPhase 3
44
Enzastaurin HCLEli LillyPhase 2
35
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25
pemetrexed + gemcitabineEli LillyPhase 2
35
ALIMTA + CarboplatinEli LillyPhase 2
35
Tomivosertib + Pembrolizumab + PemetrexedeFFECTOR TherapeuticsPhase 2
29
Divarasib + Pembrolizumab + Pemetrexed + Carboplatin + CisplatinChugai PharmaceuticalPhase 3
47