sacubitril/valsartan (LCZ696) + enalapril + matching placebo sacubitril/valsartan (LCZ696) + matching placebo enalapril
ApprovedCompleted 0 watching 0 views this week🔥 Hot
85
Development Stage
✓
Pre-clinical✓
Phase 1✓
Phase 2✓
Phase 35
ApprovedIndication / Disease
Heart Failure, Reduced Ejection Fraction
Conditions
Heart Failure, Reduced Ejection Fraction
Trial Timeline
Dec 16, 2016 → Mar 19, 2018
NCT ID
NCT02970669About sacubitril/valsartan (LCZ696) + enalapril + matching placebo sacubitril/valsartan (LCZ696) + matching placebo enalapril
sacubitril/valsartan (LCZ696) + enalapril + matching placebo sacubitril/valsartan (LCZ696) + matching placebo enalapril is a approved stage product being developed by Novartis for Heart Failure, Reduced Ejection Fraction. The current trial status is completed. This product is registered under clinical trial identifier NCT02970669. Target conditions include Heart Failure, Reduced Ejection Fraction.
Hype Score Breakdown
Clinical
30
Activity
20
Company
10
Novelty
10
Community
12
Clinical Trials (1)
| NCT ID | Phase | Status |
|---|---|---|
| NCT02970669 | Approved | Completed |
Competing Products
20 competing products in Heart Failure, Reduced Ejection Fraction
| Product | Company | Stage | Hype Score |
|---|---|---|---|
| IV diuretic | Nuwellis | Pre-clinical | 15 |
| IV Loop Diuretics | Nuwellis | Pre-clinical | 15 |
| Stepped pharmacologic care | Nuwellis | Phase 3 | 69 |
| IV Loop Diuretics (LD) | Nuwellis | Pre-clinical | 15 |
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| TRV027 Dose #1 + TRV027 Dose #2 + TRV027 Dose #3 + Placebo | Trevena | Phase 2 | 44 |
| TRV120027 + Placebo | Trevena | Phase 1/2 | 33 |
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| INXN-4001 | Precigen | Phase 1 | 28 |
| LY3461767 + Placebo | Eli Lilly | Phase 1 | 33 |
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| Olmesartan | Daiichi Sankyo | Phase 3 | 77 |
| Carperitide + Placebo | Daiichi Sankyo | Phase 2 | 52 |
| Edoxaban | Daiichi Sankyo | Pre-clinical | 23 |
| Regadenoson | Astellas Pharma | Phase 1 | 33 |
| Advagraf + Prograf | Astellas Pharma | Phase 2 | 52 |
| FK506E | Astellas Pharma | Phase 3 | 77 |