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naloxegol + non-PAMORA laxative

Pre-clinicalTerminated
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Interest: 18/100
18
Hype Score

Development Stage

1
Pre-clinical
2
Phase 1
3
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Opioid Induced Constipation

Conditions

Opioid Induced Constipation

Trial Timeline

Sep 1, 2016 → Nov 1, 2021

NCT ID
NCT02813369

About naloxegol + non-PAMORA laxative

naloxegol + non-PAMORA laxative is a pre-clinical stage product being developed by Kyowa Kirin for Opioid Induced Constipation. The current trial status is terminated. This product is registered under clinical trial identifier NCT02813369. Target conditions include Opioid Induced Constipation.

What happened to similar drugs?

8 of 20 similar drugs in Opioid Induced Constipation were approved

Approved (8) Terminated (6) Active (7)
✅Naldemedine + PlaceboShionogiApproved
✅Polyethylene Glycol 3350 + MovantikAstraZenecaApproved
✅Naltrexone for extended-release injectable suspension + Oral naltrexoneAlkermesApproved
✅NaltrexoneAlkermesApproved
✅VIVITROL 380mgAlkermesApproved
✅methylnaltrexone + placeboBausch HealthApproved
✅Methylnaltrexone bromideBausch HealthApproved

Hype Score Breakdown

Clinical
3
Activity
0
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT02813369Pre-clinicalTerminated

Competing Products

20 competing products in Opioid Induced Constipation

See all competitors
ProductCompanyStageHype Score
SUBLOCADEIndivior PLCPhase 3
29
SUBLOCADEIndivior PLCPhase 3
29
ASP8082 + morphine + PlaceboAstellas PharmaPhase 1
29
ASP8062 + Placebo ASP8062 + buprenorphine/naloxoneAstellas PharmaPhase 1
29
ASP8062 + Placebo ASP8062 + buprenorphine/naloxoneAstellas PharmaPhase 2
27
Naldemedine + PlaceboShionogiPhase 3
40
Naldemedine + PlaceboShionogiApproved
50
NaldemedineShionogiPhase 1/2
39
Naldemedine + PlaceboShionogiPhase 3
40
Placebo + NaldemedineShionogiPhase 2
35
Naldemedine + PlaceboShionogiPhase 3
40
Naldemedine + PlaceboShionogiPhase 2
35
NaloxegolKyowa KirinPre-clinical
26
NaloxegolKyowa KirinPre-clinical
26
NaloxegolKyowa KirinPre-clinical
26
Brenipatide + Placebo + BuprenorphineEli LillyPhase 2
42
NKTR-118 + NKTR-118 + PlaceboAstraZenecaPhase 3
32
Naloxegol + NaloxegolAstraZenecaPhase 1
29
NKTR-118 + Usual careAstraZenecaPhase 3
40
Polyethylene Glycol 3350 + MovantikAstraZenecaApproved
43