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Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow fever vaccine + Measles, mumps, and rubella (MMR) vaccine + Pneumococcal Conjugated Vaccine + Hepatitis A Pediatric Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow Fever Vaccine + Placebo (NaCl) + Measles, mumps, and rubella vaccine + Pneumococcal Conjugated Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Hepatitis A Pediatric Vaccine

Phase 3Completed
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Interest: 40/100
40
Hype Score

Development Stage

✓
Pre-clinical
✓
Phase 1
✓
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Dengue

Conditions

Dengue, Dengue Hemorrhagic Fever, Yellow Fever

Trial Timeline

Sep 7, 2011 → Sep 2, 2013

NCT ID
NCT01436396

About Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow fever vaccine + Measles, mumps, and rubella (MMR) vaccine + Pneumococcal Conjugated Vaccine + Hepatitis A Pediatric Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow Fever Vaccine + Placebo (NaCl) + Measles, mumps, and rubella vaccine + Pneumococcal Conjugated Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Hepatitis A Pediatric Vaccine

Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow fever vaccine + Measles, mumps, and rubella (MMR) vaccine + Pneumococcal Conjugated Vaccine + Hepatitis A Pediatric Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Live, attenuated dengue serotype 1, 2, 3, and 4 virus + Yellow Fever Vaccine + Placebo (NaCl) + Measles, mumps, and rubella vaccine + Pneumococcal Conjugated Vaccine + Diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae vaccine + Hepatitis A Pediatric Vaccine is a phase 3 stage product being developed by Sanofi for Dengue. The current trial status is completed. This product is registered under clinical trial identifier NCT01436396. Target conditions include Dengue, Dengue Hemorrhagic Fever, Yellow Fever.

What happened to similar drugs?

0 of 8 similar drugs in Dengue were approved

Approved (0) Terminated (1) Active (7)
🔄Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Placebo: NaCl 0.9%SanofiPhase 3
❌CYD Dengue Vaccine + Tdap: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine adsorbed + Tdap: Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbedSanofiPhase 3
🔄Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus + Placebo: NaCl 0.9%SanofiPhase 3
🔄Live, attenuated, dengue serotype 1, 2, 3, 4 virus + Placebo: (NaCl) 0.9% solutionSanofiPhase 3
🔄CYD Dengue Vaccine + CYD Dengue Vaccine + Human Papillomavirus Quadrivalent [Types 6, 11, 16, and 18] Vaccine, Recombinant.SanofiPhase 3
🔄Live, attenuated, dengue serotype 1, 2, 3, 4 virus + Placebo: Sodium chloride (NaCl) 0.9%SanofiPhase 3
🔄CYD Dengue Vaccine + CYD Dengue Vaccine + Human Papillomavirus Bivalent [Types 16 and 18] Vaccine, Recombinant + Human Papillomavirus Bivalent [Types 16 and 18] Vaccine, RecombinantSanofiPhase 3

Hype Score Breakdown

Clinical
17
Activity
8
Company
15
Novelty
0
Community
0

Clinical Trials (1)

NCT IDPhaseStatus
NCT01436396Phase 3Completed

Competing Products

20 competing products in Dengue

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balapiravir [RO4588161] + placeboRochePhase 1
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Dengue Tetravalent Vaccine, LiveSanofiPre-clinical
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Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, & 4 virus + Placebo: NaCl 0.9%SanofiPhase 3
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Live, attenuated, recombinant dengue serotype 1 , 2, 3 , and 4 virus + NaCl 0.9% + Tetanus toxoid, reduced diphtheria toxoid, acellular pertussis vaccine adsorbed + Meningococcal A+C vaccineSanofiPhase 2
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Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus + Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus + Yellow FeverSanofiPhase 2
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Tetravalent CYD Dengue Vaccine , 5555 formulation + Tetravalent CYD Dengue Vaccine , 5553 formulation + Tetravalent CYD Dengue Vaccine, 4444 formulationSanofiPhase 2
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CYD Dengue Vaccine + Tdap: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine adsorbed + Tdap: Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine adsorbedSanofiPhase 3
32
Live, attenuated, recombinant dengue serotypes 1, 2, 3, and 4 virus + Placebo: NaCl 0.9%SanofiPhase 3
40
Live, attenuated, dengue serotype 1, 2, 3, 4 virus + Placebo: (NaCl) 0.9% solutionSanofiPhase 3
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CYD Dengue Vaccine + CYD Dengue Vaccine + Human Papillomavirus Quadrivalent [Types 6, 11, 16, and 18] Vaccine, Recombinant.SanofiPhase 3
40
CYD dengue vaccine serotypes (1, 2, 3, 4). + Meningococcal Polysaccharide A+C; NaCl; Typhoid Vi polysaccharideSanofiPhase 2
35
CYD Dengue Vaccine + Placebo (Sodium chloride 0.9%)SanofiPhase 2
35
CYD Dengue Vaccine + Inactivated rabies virus vaccine + PlaceboSanofiPhase 2
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