evinacumab

Phase 3Completed
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76
Hype Score

Development Stage

โœ“
Pre-clinical
โœ“
Phase 1
โœ“
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Homozygous Familial Hypercholesterolemia

Conditions

Homozygous Familial Hypercholesterolemia

Trial Timeline

Mar 13, 2018 โ†’ Apr 13, 2023

About evinacumab

evinacumab is a phase 3 stage product being developed by Regeneron Pharmaceuticals for Homozygous Familial Hypercholesterolemia. The current trial status is completed. This product is registered under clinical trial identifier NCT03409744. Target conditions include Homozygous Familial Hypercholesterolemia.

Hype Score Breakdown

Clinical
27
Activity
18
Company
9
Novelty
9
Community
10

Clinical Trials (4)

NCT IDPhaseStatus
NCT06500598Pre-clinicalCompleted
NCT04863014Phase 2Terminated
NCT04233918Phase 3Completed
NCT03409744Phase 3Completed

Competing Products

20 competing products in Homozygous Familial Hypercholesterolemia

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InclisiranNovartisPhase 3
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41
Inclisiran + PlaceboNovartisPhase 3
77
Evolocumab + PlaceboAmgenPhase 2/3
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evolocumabAmgenApproved
84
MBX-8025 50 mg (Dose Escalation Period 1) + MBX-8025 50 mg or 100 mg (Dose Escalation Period 2) + MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)Gilead SciencesPhase 2
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IBI306 + IBI306Innovent BiologicsPhase 2/3
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BMS-986504 + [14C]-BMS-986504Bristol Myers SquibbPhase 1
32
Lumacaftor Plus Ivacaftor Combination + Ivacaftor + PlaceboVertex PharmaceuticalsPhase 3
76
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76
Lumacaftor Plus Ivacaftor Combination + IvacaftorVertex PharmaceuticalsPhase 3
76
Alirocumab + PlaceboSanofiPhase 3
76
AK102 + Statins + EzetimibeAkesoPhase 2
51
EvinacumabRegeneron PharmaceuticalsPhase 3
76
REGN1500 250 mg SC/15 mg/kg IV/450 mg SCRegeneron PharmaceuticalsPhase 2
51
EvinacumabRegeneron PharmaceuticalsPre-clinical
22