Dasatinib + Osimertinib

Phase 1/2Terminated

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Interest: 24/100

Hype Score

Development Stage

✓

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

EGFR Gene Mutation

Conditions

EGFR Gene Mutation, Nonsmall Cell Lung Cancer

Trial Timeline

Oct 1, 2016 → Mar 3, 2023

NCT ID

NCT02954523

About Dasatinib + Osimertinib

Dasatinib + Osimertinib is a phase 1/2 stage product being developed by AstraZeneca for EGFR Gene Mutation. The current trial status is terminated. This product is registered under clinical trial identifier NCT02954523. Target conditions include EGFR Gene Mutation, Nonsmall Cell Lung Cancer.

What happened to similar drugs?

1 of 7 similar drugs in EGFR Gene Mutation were approved

Approved (1) Terminated (1) Active (5)

✅GefitinibAstraZenecaApproved

🔄AZD9291 + MEDI4736AstraZenecaPhase 3

🔄AZD9291 80mg oral each dayAstraZenecaPhase 3

🔄AZD9291 80 mg/40 mg + placebo + Placebo Erlotinib 150/100mg + Placebo Gefitinib 250 mg + Erlotinib 150/100 mg + Gefitinib 250 mg + Placebo AZD9291 80 mg/ 40 mgAstraZenecaPhase 3

🔄Cetuximab + FOLFIRI (5-Fluorouracil, Folinic acid, Irinotecan)MerckPhase 3

❌ERLOTINIB WITH CHEMOTHERAPY + CHEMOTHERAPY ONLYRochePhase 3

🔄Dacomitinib (PF-00299804) + GefitinibPfizerPhase 3

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (1)

NCT ID	Phase	Status	Start	Completion	Indication
NCT02954523	Phase 1/2	Terminated	Oct 1, 2016	Mar 3, 2023	EGFR Gene Mutation

Competing Products

20 competing products in EGFR Gene Mutation

See all competitors

Product	Company	Stage	Hype Score
YH25448	Yuhan	Phase 1/2	32
YH32364	Yuhan	Phase 1/2	39
Datopotamab deruxtecan	Daiichi Sankyo	Pre-clinical	26
HER3-DXd	Daiichi Sankyo	Pre-clinical	26
ASP8273	Astellas Pharma	Phase 2	27
radio-labeled naquotinib + naquotinib	Astellas Pharma	Phase 1	21
erlotinib	Astellas Pharma	Phase 1	29
ASP8273 Capsules + ASP8273 Capsules A	Astellas Pharma	Phase 2	27
famitinib po + HS-10296 po	Jiangsu Hengrui Medicine	Phase 2	31
ABT-414	AbbVie	Pre-clinical	26
AZD9291 40 mg + AZD9291 80 mg	AstraZeneca	Phase 1	29
Osimertinib-based adaptive treatment + Osimertinib 80 MG	AstraZeneca	Phase 2	42
AZD9291 + MEDI4736	AstraZeneca	Phase 3	40
EGFR TKIs (gefitinib, erlotinib, afatinib, et al)	AstraZeneca	Pre-clinical	22
AZD9291	AstraZeneca	Pre-clinical	26
Osimertinib	AstraZeneca	Phase 2	35
AZD9291 80mg oral each day	AstraZeneca	Phase 3	36
Tremelimumab + Durvalumab	AstraZeneca	Phase 2	31
Osimertinib	AstraZeneca	Phase 2	35
AZD3759 + AZD9291	AstraZeneca	Phase 1	29