Brexpiprazole

Phase 3Completed
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Interest: 37/100
37
Hype Score

Development Stage

Pre-clinical
Phase 1
Phase 2
4
Phase 3
5
Approved
Indication / Disease

Agitation Associated With Alzheimer's Dementia

Conditions

Agitation Associated With Alzheimer's Dementia, Alzheimer Dementia

Trial Timeline

May 16, 2018 → Jun 1, 2022

About Brexpiprazole

Brexpiprazole is a phase 3 stage product being developed by Lundbeck for Agitation Associated With Alzheimer's Dementia. The current trial status is completed. This product is registered under clinical trial identifier NCT03548584. Target conditions include Agitation Associated With Alzheimer's Dementia, Alzheimer Dementia.

What happened to similar drugs?

2 of 13 similar drugs in Agitation Associated With Alzheimer's Dementia were approved

Approved (2) Terminated (2) Active (9)
Dexmedetomidine + Lorazepam 2 MG/MLBioXcel TherapeuticsApproved
🔄Brexpiprazole, OPC-34712LundbeckPhase 3
🔄AXS-05 (dextromethorphan-bupropion) + PlaceboAxsome TherapeuticsPhase 3
AXS-05 (dextromethorphan-bupropion)Axsome TherapeuticsPhase 3
🔄AXS-05 + PlaceboAxsome TherapeuticsPhase 3

Hype Score Breakdown

Clinical
17
Activity
8
Company
12
Novelty
0
Community
0

Clinical Trials (11)

NCT IDPhaseStatus
NCT05504486ApprovedWithdrawn
NCT04830215ApprovedCompleted
NCT04258839Phase 3Completed
NCT03548584Phase 3Completed
NCT03287869Phase 3Completed
NCT03292848Phase 1Completed
NCT03238326Phase 3Completed
NCT01944969Phase 3Terminated
NCT01942785Phase 3Completed
NCT01942733Phase 3Completed
NCT01810783Phase 3Completed

Competing Products

20 competing products in Agitation Associated With Alzheimer's Dementia

See all competitors
ProductCompanyStageHype Score
ONO-2020 + PlaceboOno PharmaceuticalPhase 2
42
Quetiapine + Haloperidol + Lorazepam + CogentinAstraZenecaApproved
43
Brexpiprazole, OPC-34712LundbeckPhase 3
37
Brexpiprazole, OPC-34712 + Placebo Oral TabletLundbeckPhase 3
37
AXS-05 (dextromethorphan-bupropion) + PlaceboAxsome TherapeuticsPhase 3
37
AXS-05 + Bupropion + PlaceboAxsome TherapeuticsPhase 2/3
35
AXS-05 (dextromethorphan-bupropion)Axsome TherapeuticsPhase 3
29
AXS-05 + PlaceboAxsome TherapeuticsPhase 3
37
AXS-05 + PlaceboAxsome TherapeuticsPhase 3
37
Pimavanserin 34 mg + Pimavanserin 20 mgAcadia PharmaceuticalsPhase 2
24
PimavanserinAcadia PharmaceuticalsPhase 2
32
Sublingual film containing Dexmedetomidine (BXCL501) + Placebo FilmBioXcel TherapeuticsPhase 3
30
BXCL501 + Matching PlaceboBioXcel TherapeuticsPhase 3
22
Sublingual film containing BXCL501 (Dexmedetomidine) + Placebo filmBioXcel TherapeuticsPhase 1
19
BXCL501 + Matching PlaceboBioXcel TherapeuticsPhase 3
30
BXCL501 + Matching PlaceboBioXcel TherapeuticsPhase 3
30
Sublingual film containing dexmedetomidine (BXCL501) + Placebo FilmBioXcel TherapeuticsPhase 3
30
BXCL501 + BXCL501 + Placebo filmBioXcel TherapeuticsPhase 2
17
BXCL501 + Placebo filmBioXcel TherapeuticsPhase 2
17
Sublingual film containing Dexmedetomidine + Sublingual Placebo FilmBioXcel TherapeuticsPhase 1/2
22