Baricitinib

Pre-clinicalCompleted

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Hype Score

Development Stage

Pre-clinical

Phase 1

Phase 2

Phase 3

Approved

Indication / Disease

Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE)

Conditions

Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI), Aicardi-Goutières Syndrome (AGS)

Trial Timeline

— → —

NCT ID

NCT01724580

About Baricitinib

Baricitinib is a pre-clinical stage product being developed by Eli Lilly for Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE). The current trial status is completed. This product is registered under clinical trial identifier NCT01724580. Target conditions include Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI).

Hype Score Breakdown

Clinical

Activity

Company

Novelty

Community

Clinical Trials (10)

NCT ID	Phase	Status	Start	Completion	Indication
NCT01724580	Pre-clinical	Completed	—	—	Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE)
NCT06797310	Phase 2	Recruiting	Jan 23, 2025	Dec 31, 2026	Alopecia Areata
NCT05074420	Phase 3	Terminated	Dec 21, 2021	Nov 4, 2024	Covid19
NCT04517253	Phase 2/3	Terminated	Oct 27, 2020	Nov 28, 2024	Nakajo-Nishimura Syndrome
NCT03921554	Phase 2	Completed	Jun 3, 2019	Mar 25, 2024	Aicardi Goutieres Syndrome
NCT03773965	Phase 3	Recruiting	Apr 5, 2019	Jul 1, 2031	Juvenile Idiopathic Arthritis
NCT03559270	Phase 3	Terminated	Jun 27, 2018	Jun 13, 2022	Atopic Dermatitis
NCT03026504	Phase 2	Completed	Mar 9, 2017	Apr 12, 2021	Arteritis, Giant Cell
NCT02263911	Phase 1	Completed	Nov 1, 2014	Dec 1, 2014	Healthy Participants
NCT01870388	Phase 1	Completed	Jun 1, 2013	Jul 1, 2013	Liver Diseases

Competing Products

20 competing products in Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE)

See all competitors

Product	Company	Stage	Hype Score
macitentan 10 mg	BML, Inc.	Phase 3	76
KPL-716 + Placebo	Kiniksa Pharmaceuticals	Phase 2	47
TERN-701	Terns Pharmaceuticals	Phase 1/2	38
Fludarabine + Cyclophosphamide + PRGN-3007	Precigen	Phase 1	28
LY3556050 + Placebo	Eli Lilly	Phase 2	52
THB001	Third Harmonic Bio	Phase 1	25
Briquilimab	Jasper Therapeutics	Phase 1/2	33
Briquilimab	Jasper Therapeutics	Phase 1/2	33
Briquilimab	Jasper Therapeutics	Phase 2	44
Empagliflozin + Matching placebo	Eli Lilly	Phase 3	77
LY3461767 + Placebo	Eli Lilly	Phase 1	33
Pirtobrutinib + Venetoclax + Rituximab	Eli Lilly	Phase 3	77
LY3526318 + Placebo	Eli Lilly	Phase 2	52
Pirtobrutinib	Eli Lilly	Phase 2	52
Ibrutinib + LY3214996	Eli Lilly	Phase 1	33
Pirtobrutinib + Acalabrutinib	Eli Lilly	Phase 2	52
LYR-210	Lyra Therapeutics	Phase 2	44
LYR-220 Design 1 (Part 1 only) + LYR-220 Design 2 (Part 1 and Part 2) + Bilateral sham procedure control (Part 2)	Lyra Therapeutics	Phase 2	44
480 Mometasone Furoate Sinus Drug Depot	Lyra Therapeutics	Phase 1	25
LYR-210 + Sham procedure control	Lyra Therapeutics	Phase 3	69

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