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Vispacabtagene regedleucel (vispa-cel, CB-010)

Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (r/r B-NHL)

Key Facts

Indication
Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (r/r B-NHL)
Phase
Phase 1
Status
Active
Company

About Caribou Biosciences

Caribou Biosciences, co-founded by Nobel laureate Jennifer Doudna, is a clinical-stage biotech focused on developing allogeneic CAR-T cell therapies using its proprietary chRDNA genome-editing platform. The company's mission is to create readily available, 'off-the-shelf' cell therapies that address the manufacturing complexities, high costs, and delays associated with personalized autologous treatments. Its strategy centers on 'armoring' these therapies through multiplex gene editing to enhance persistence and activity, with multiple Phase 1 clinical trials underway for B-cell non-Hodgkin lymphoma and multiple myeloma. Caribou aims to translate its foundational CRISPR science into transformative medicines for hematologic cancers.

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Other Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (r/r B-NHL) Drugs

DrugCompanyPhase
UCART20x22CellectisPhase 1/2a