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UBX1325 (foselutoclax)

Diabetic Macular Edema (DME)

Phase 2bDiscontinuedNCT05614666 (BEHOLD)

Key Facts

Indication
Diabetic Macular Edema (DME)
Phase
Phase 2b
Status
Discontinued
Company

About Unity Biotechnology

Unity Biotechnology was founded on groundbreaking academic research into cellular senescence as a root cause of age-related diseases. Its mission was to develop selective senolytic medicines, initially focusing on localized delivery for ophthalmologic conditions like diabetic macular edema and neurodegenerative diseases. Despite promising early-stage clinical data and raising significant capital, the company faced clinical setbacks, pivoted its strategy, and ultimately ceased operations in 2024, marking the end of a prominent early player in the longevity therapeutics field.

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About Unity Biotechnology

Unity Biotechnology was founded on groundbreaking academic research into cellular senescence as a root cause of age-related diseases. Its mission was to develop selective senolytic medicines, initially focusing on localized delivery for ophthalmologic conditions like diabetic macular edema and neurodegenerative diseases. Despite promising early-stage clinical data and raising significant capital, the company faced clinical setbacks, pivoted its strategy, and ultimately ceased operations in 2024, marking the end of a prominent early player in the longevity therapeutics field.

View full company profile

Other Diabetic Macular Edema (DME) Drugs

DrugCompanyPhase
CLS-AXClearside BiomedicalPreclinical
OCS-01OculisPhase 3
Oral K9Inflammasome TherapeuticsPhase I
Ixoberogene soroparvovec (Ixo-vec)Adverum BiotechnologiesPhase 2
Allgenesis Phase 2 DME Trial SupportVoxeleronPhase 2
AvoralstatBioCryst PharmaceuticalsPhase 2
DURAVYU™ (EYP-1901)EyePoint PharmaceuticalsPhase 3
Sozinibercept (OPT-302)OptheaPhase 2
ONS-5010 / LYTENAVA™ (bevacizumab-vikg)Outlook TherapeuticsPhase 3