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TK-6302

PRAME-positive solid tumors

Pre-clinicalActive

Key Facts

Indication
PRAME-positive solid tumors
Phase
Pre-clinical
Status
Active
Company

About T-Knife Therapeutics

T-Knife Therapeutics is a private, pre-clinical stage biotech company pioneering next-generation TCR-T cell therapies for solid tumors. Its core differentiation lies in the proprietary MyT™ platform, which generates fully human, high-affinity TCRs, combined with internally developed enhancements like novel CD8 coreceptors and switch receptors. The company's lead candidate, TK-6302, targeting the PRAME antigen, is planned to enter Phase 1 trials in 2026, positioning T-Knife in the competitive but high-potential field of engineered cell therapies for oncology. With seasoned leadership and strong academic roots from the Max Delbrück Center and Charité in Berlin, T-Knife is advancing a pipeline aimed at addressing high unmet medical needs.

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Therapeutic Areas

Other PRAME-positive solid tumors Drugs

DrugCompanyPhase
IMA203Immatics BiotechnologiesPhase 1/2
IMA203CD8Immatics BiotechnologiesPhase 1/2
IMA402Immatics BiotechnologiesPhase 1/2
IMA402 (TCER®)ImmaticsPhase 1/2
Anzu-cel (IMA203C)ImmaticsPhase 1