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TCR Library Program

Various Solid Tumors

DiscoveryActive

Key Facts

Indication
Various Solid Tumors
Phase
Discovery
Status
Active
Company

About Medigene

Medigene is a clinical-stage biotech focused on engineering T-cell receptor (TCR)-modified T-cell therapies for solid tumors, a notoriously difficult-to-treat area. Its strategy is built on two proprietary technology pillars: a high-throughput TCR discovery platform and a PD1-41BB costimulatory switch receptor designed to enhance T-cell persistence and function. The company has advanced its lead candidate, MDG1011, into Phase I/II clinical trials and is actively building a pipeline of novel TCRs through internal discovery and partnerships. As a publicly traded entity, Medigene aims to validate its platform and establish a leadership position in the evolving TCR-T cell therapy landscape.

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Therapeutic Areas

Other Various Solid Tumors Drugs

DrugCompanyPhase
NUC-8232NuCanaPhase 1
Solid Tumor ProfilingDiatech PharmacogeneticsCommercial
BAVENCIO (avelumab)EMD SeronoApproved
Jemperli (dostarlimab) combinationsGSKPhase 3
FoundationOne®CDx Indication ExpansionFoundation MedicineApproved/Commercial
FoundationOne®Liquid CDx Indication ExpansionFoundation MedicineApproved/Commercial
Taiho Oncology PipelineOtsuka HoldingsMultiple (I-III)
Lenvatinib + PembrolizumabEisaiPhase 3 / Marketed
PD-1/PD-L1 InhibitorPeptiDreamPhase 1
Cadonilimab (AK104)AkesoPhase III
TEVIMBRA (tislelizumab)BeOne MedicinesApproved / Phase 3
Early I-O PipelineIpsenPre-clinical / Phase 1