Guardant Health

Guardant Health

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Private Company

Total funding raised: $738M

Market Cap: $12.6BFounded: 2013Employees: 1000-5000HQ: Redwood City, United States

Overview

Guardant Health's mission is to transform cancer care by unlocking critical insights from a simple blood draw, shifting the paradigm from reactive to proactive, data-driven management. The company has achieved significant clinical adoption with over 500,000 commercial tests performed by more than 12,000 oncologists and secured FDA approval for its colorectal cancer screening test, Guardant Shield. Its strategy is built on a three-pillar business model spanning Clinical diagnostics, Biopharma solutions, and a high-growth Screening franchise, all powered by its proprietary liquid biopsy and multi-omic platform, Guardant Infinity.

OncologyCancer Screening

Technology Platform

Proprietary liquid biopsy platform analyzing circulating tumor DNA (ctDNA) for genomic and epigenomic profiling, enabling cancer detection, treatment selection, and monitoring from a simple blood draw.

Funding History

5
Total raised:$738M
IPO$238M
Series D$360M
Series C$100M
Series B$30M

Opportunities

The multi-billion dollar markets for colorectal and lung cancer screening represent near-term growth vectors, while the long-term opportunity in multi-cancer early detection (MCED) could exceed $100 billion globally.
Guardant's unified platform for both advanced cancer and screening creates unique data synergies and a competitive moat.

Risk Factors

Key risks include regulatory and reimbursement hurdles for new screening tests, intense competition in the early detection space from well-funded rivals like Grail and Exact Sciences, and the significant execution risk associated with scaling patient and physician adoption of blood-based screening.

Competitive Landscape

Guardant faces competition from Foundation Medicine/Roche in advanced cancer profiling, Exact Sciences in CRC screening, and Grail (Illumina) in multi-cancer early detection. Its differentiation lies in its commercial scale in liquid biopsy, its multi-omic Infinity platform, and its integrated business model across clinical, biopharma, and screening segments.

Company Timeline

2013Founded

Founded in Redwood City, United States

2015Series C

Series C: $100.0M

2017Series D

Series D: $360.0M

2018IPO

IPO — $238.0M