Small Molecule Drug Discovery

About Zafrens

Zafrens is pioneering a next-generation, high-throughput experimental platform that uniquely links phenotypic imaging with single-cell genomic sequencing at an unprecedented scale. Its core innovation, Z-Screen, uses nanofabrication to run millions of nanoliter-volume experiments on a benchtop instrument without robotics, compressing drug discovery timelines. The platform's universal workflow is applicable to small molecules, biologics, cell therapies, and gene therapies, with current efforts focused on internal small molecule discovery and T cell analysis. By generating massive, causally-linked multimodal datasets, Zafrens aims to unlock novel therapeutic insights and accelerate the development of all therapeutic modalities.

Therapeutic Areas