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SAB-142

Type 1 Diabetes

Pre-clinicalActive

Key Facts

Indication
Type 1 Diabetes
Phase
Pre-clinical
Status
Active
Companies

About SAB BIO

SAB BIO is a private, pre-revenue biotech founded in 2018, advancing a novel therapeutic approach for Type 1 Diabetes. The company's pipeline is centered on SAB-142, a disease-modifying therapy intended to delay disease progression by modulating the autoimmune attack on pancreatic beta cells. Operating in the high-need autoimmune and diabetes space, SAB BIO represents an early-stage venture with a focused scientific strategy aimed at altering the course of T1D. Its progress is guided by an established leadership and clinical advisory board.

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About SAB Biotherapeutics

SAB Biotherapeutics' mission is to leverage its proprietary DiversitAb™ platform to develop a new class of fully human polyclonal antibody therapeutics. Its key achievement is the creation of a validated, scalable production system using transgenic cattle, which has advanced multiple candidates into clinical trials, including a program for COVID-19. The company's strategy is to clinically validate its platform in autoimmune disease, starting with type 1 diabetes, and expand into other areas of high unmet need where polyclonal antibodies offer a differentiated therapeutic profile. As a public company, SAB is focused on executing its clinical milestones to demonstrate proof-of-concept and attract strategic partnerships.

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Other Type 1 Diabetes Drugs

DrugCompanyPhase
eRapaBiodexa PharmaceuticalsPreclinical
ImmCelz™Creative Medical Technology HoldingsClinical Trial
Adimune (ADi-001/002)AditxtPreclinical / Early Clinical
MSC‑DiabetesAdvancellsPhase 1
BioChaperone® Lispro (THDB0206)AdociaPhase 3
AdoShell® Islet Cell TherapyAdociaPreclinical
Pediatric Indications (<2 years)Tandem DiabetesResearch
Icovamenib (BMF-219)Biomea FusionPhase 2
Undisclosed Novel StrategyCG ScientificPre-clinical
SotagliflozinLexicon PharmaceuticalsPhase 3
Stem Cell-Derived Beta CellsBioTalentumPre-clinical
NICHEContinuity BiosciencesPre-clinical