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Icovamenib (BMF-219)

Type 2 Diabetes (Insulin-Deficient)

Phase 2Active, EnrollingCOVALENT-211

Key Facts

Indication
Type 2 Diabetes (Insulin-Deficient)
Phase
Phase 2
Status
Active, Enrolling
Company

About Biomea Fusion

Biomea Fusion is a clinical-stage biotechnology company dedicated to developing covalent small molecule therapies for diabetes and obesity, with the ambitious goal of curing disease. Its lead asset, icovamenib, is a novel oral menin inhibitor designed to regenerate pancreatic beta cells and is advancing through multiple Phase II trials in type 1 and type 2 diabetes. The company's strategy leverages its integrated covalent inhibitor platform to create highly selective, durable therapies, positioning it to address significant unmet needs in large metabolic markets. Key near-term catalysts include topline 26-week data from two Phase II studies in type 2 diabetes expected in Q4 2026.

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About Biomea Fusion

Biomea Fusion is a clinical-stage biotechnology company dedicated to developing covalent small molecule therapies for diabetes and obesity, with the ambitious goal of curing disease. Its lead asset, icovamenib, is a novel oral menin inhibitor designed to regenerate pancreatic beta cells and is advancing through multiple Phase II trials in type 1 and type 2 diabetes. The company's strategy leverages its integrated covalent inhibitor platform to create highly selective, durable therapies, positioning it to address significant unmet needs in large metabolic markets. Key near-term catalysts include topline 26-week data from two Phase II studies in type 2 diabetes expected in Q4 2026.

View full company profile

About Biomea Fusion

Biomea Fusion is a clinical-stage biotechnology company dedicated to developing covalent small molecule therapies for diabetes and obesity, with the ambitious goal of curing disease. Its lead asset, icovamenib, is a novel oral menin inhibitor designed to regenerate pancreatic beta cells and is advancing through multiple Phase II trials in type 1 and type 2 diabetes. The company's strategy leverages its integrated covalent inhibitor platform to create highly selective, durable therapies, positioning it to address significant unmet needs in large metabolic markets. Key near-term catalysts include topline 26-week data from two Phase II studies in type 2 diabetes expected in Q4 2026.

View full company profile

About Biomea Fusion

Biomea Fusion is a clinical-stage biotechnology company dedicated to developing covalent small molecule therapies for diabetes and obesity, with the ambitious goal of curing disease. Its lead asset, icovamenib, is a novel oral menin inhibitor designed to regenerate pancreatic beta cells and is advancing through multiple Phase II trials in type 1 and type 2 diabetes. The company's strategy leverages its integrated covalent inhibitor platform to create highly selective, durable therapies, positioning it to address significant unmet needs in large metabolic markets. Key near-term catalysts include topline 26-week data from two Phase II studies in type 2 diabetes expected in Q4 2026.

View full company profile

Therapeutic Areas