Rusfertide (PTG-300)
Polycythemia Vera
Phase 3NDA filing EOY '25
Key Facts
About Protagonist Therapeutics
Protagonist Therapeutics is a leader in peptide-based drug discovery, leveraging its proprietary Vectrix™ platform to overcome historical challenges of oral bioavailability and stability. The company has achieved significant milestones, including the FDA approval of icotrokinra for psoriasis and a pending NDA for rusfertide in polycythemia vera. Its strategy combines internal development of wholly-owned assets with strategic partnerships, like the one with Janssen for icotrokinra, to build a diversified, multi-indication portfolio.
View full company profileTherapeutic Areas
Other Polycythemia Vera Drugs
| Drug | Company | Phase |
|---|---|---|
| Rusfertide | Takeda Pharmaceutical | NDA Submitted |
| Jakafi (ruxolitinib) | Incyte | Marketed |
| DISC-3405 | Disc Medicine | Phase 2b |