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Rusfertide (PTG-300)

Polycythemia Vera

Phase 3NDA filing EOY '25

Key Facts

Indication
Polycythemia Vera
Phase
Phase 3
Status
NDA filing EOY '25
Company

About Protagonist Therapeutics

Protagonist Therapeutics is a leader in peptide-based drug discovery, leveraging its proprietary Vectrix™ platform to overcome historical challenges of oral bioavailability and stability. The company has achieved significant milestones, including the FDA approval of icotrokinra for psoriasis and a pending NDA for rusfertide in polycythemia vera. Its strategy combines internal development of wholly-owned assets with strategic partnerships, like the one with Janssen for icotrokinra, to build a diversified, multi-indication portfolio.

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Other Polycythemia Vera Drugs

DrugCompanyPhase
RusfertideTakeda PharmaceuticalNDA Submitted
Jakafi (ruxolitinib)IncyteMarketed
DISC-3405Disc MedicinePhase 2b